Pattsi
Forum Replies Created
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clove oil, Lidocaine, menthol - I can see where this is going.
Are you sure you want to use menthol and clove oil? They can sting the inside of the recipient.Make sure you do the irritation test properly.
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They’ve never claimed about fingerprints, they only claim fast absorb and leaves no oily traces/film.
https://fr.loccitane.com/cr%C3%A8me-mains-karit%C3%A9,74,1,24788,959885.htm#s=24229 - they say sans aucun film gras - my French is super weak so I might missed smthing.
The fingerprints part might comes from exaggerated influencers/users reviews.
I think they did a pretty good job for that high amount of Shea butter cream.
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Sepimat series would have a superior feeling but if you only want to kill gloss and talc isn’t ideal name on the label, modified starch powder would be more cost effective in hand cream.
@Graillotion Dimethicone Crosspolymer is really good, you have to try it maybe you might have your new aha.
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low efficiency topically, IMHO alpha-arbutin is better.
quite effective in intradermal cocktail tho. -
Sorry for my curiosity and stupidity.Why 165>Montanovs? What’s the advantage of this combo? Will this form a lamellar network?Would this combo give a richer feel than 165 + linear emulsifier combo?
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@Dreamer77
Sorry I didn’t reply to your message because products we sell have to have IP under our company’s name, it seems you were not willing to let go of it and you’ve already put it on sale, you said 10,000+ jars right? if I put it under our brand it will only be a dupe of yours right?Your hyaluronidases eye serum - I am not interested, seems you may / might not understand eye bags pathophysiology thoroughly - please do correct me if I’m wrong.
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Dreamer77 said:use it on my own free will,
What?
Hyaluronidases are labeled in the European Union for the following indications: (1) as adjuvant therapy in subcutaneous drug administration, (2) to increase penetration of a local anesthetic, (3) to promote the reabsorption of contrast medium in urology, and (4) to promote reabsorption of subcutaneous hematomas. Off-label prescriptions are allowed, informed consent of the patient is required, and the related prescriptions (specifying the indication) must be reported in a medical record. In addition, the pharmacist must send a copy of the off-label prescription to the local health office and then to the Public Health Department. -
Thank you @jemolian
now I found interesting one, it’s Kylie - How can I missed it.Bis-Diglyceryl Polyacyladipate-2, Hydrogenated Polyisobutene, Diisostearyl Malate, Butyrospermum Parkii (Shea) Butter, Ozokerite, Isopropyl Palmitate, Water/Aqua/Eau, Styrene/Acrylates Copolymer, Flavor (Aroma), Cetearyl Alcohol, Punica Granatum Sterols, Stevioside, Tocopheryl Acetate, Geraniol, Cocos Nucifera (Coconut) Oil, Copernicia Cerifera (Carnauba) Wax/Copernicia Cerifera Cera, Euphorbia Cerifera (Candelilla) Wax/Candelilla Cera, Helianthus Annuus (Sunflower) Seed Oil, Citronellol, Persea Gratissima (Avocado) Oil, Citric Acid, Actinidia Chinensis (Kiwi) Seed Oil, Tocopherol
Is this formula pumpable? I have to try it.Shandong Natural Micron Pharm Tech Co., LTD - have 1 kg. in alibaba
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Diisostearyl Malate doesn’t spread well and the price is around x2 Tridecyl Trimellitate so haven’t seen it in non-pigmented formulas or maybe I’m missing some.
Diisostearyl Malate film thicker than Tridecyl Trimellitate.jemolian said:@Pharma- Parleam (Hydrogenated Polyisobutene) + Liponate TDTM (Tridecyl Trimellitate)
would win for the cost efficiency.
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Bis-Diglyceryl Polyacyladipate-2 - rich, heavy feel similar to lanolin.
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Ask your vendors who’re their targeted consumers and what they like/want, It will save you a lot of time in R&D.
Maybe let’s go for Anti-aging hand cream for 아줌마.
The youngers tend to use what their idols use so it might be harder to keep up with them, or if you can make 4 different scents/functions that will do.for some ref.
https://www.youtube.com/watch?v=ki-TpyBps0k -
Which one are we talking about?
https://www.dermastart.com/product-page/5012-sport-shield-spf-45
https://www.amazon.com/ask/questions/TxDJQNU8P4RNWX/ref=ask_ql_ql_al_hza
https://www.amazon.com/gp/product/B00IAR7Z3A/ref=ask_ql_qh_dp_hza
https://www.rejuvelle.com/products/rejuvelle-sunscreen-for-face-spf-45
https://www.amazon.ca/Aloe-Vera-Gel-Moisturizing-Nourishing/dp/B0795RRS6S
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peg-20 glyceryl triisostearate & peg-8 isostearate works well with Ethylhexyl Palmitate, you will have to find the right %.
or you can try
EMULPHARMA® ECO10 : Polyglyceryl-10 Laurate (and) Water
SALACOS® DG-158 : Polyglyceryl-2 Sesquicaprylate
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https://www.fda.gov/drugs/human-drug-compounding/compounding-laws-and-policies
https://www.fda.gov/drugs/human-drug-compounding/section-503a-federal-food-drug-and-cosmetic-act
https://www.fda.gov/drugs/human-drug-compounding/text-compounding-quality-act
https://www.fda.gov/drugs/human-drug-compounding/information-outsourcing-facilities
https://www.fda.gov/drugs/human-drug-compounding/compounding-oversight-and-compliance-actions
don’t know if these help.
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@PhilGeis @Perry Sorry, I didn’t mean to say to do the research on the whole Ayurveda and TCM, I myself think the concept of energies or elements is quite nonsense. But I will have to leave a room for the wave–particle duality quantum physics thing which I have no understanding enough to make a comment - maybe or maybe not we will have more to learn in the future.
What I meant is there interesting herbal remedy and yoga or tai chi movement which might or may have potential benefit, I would want to see a more proper method rather than observe-based study.
In US, alternative medicine, Ayurvedic and TCM - ish wellness products make quite a huge money so I can’t see a company would want to fund a research which has a potential to pop their bubble.
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Perry said:I’ll just leave this here.
https://skepticalinquirer.org/exclusive/ayurveda-ancient-superstition-not-ancient-wisdom/I find the author was quite ignorant, arrogant and prejudice against Ayurveda.
“That just about sums it up. Ayurveda is basically superstition mixed with a soupçon of practical health advice.” based her opinion on Ayurveda from only Deepak Chopra.And dishing on India was quite unfair.
“Ayurveda originated in India and is still widely used there. In a list of longevity by country, India ranked 125th. That suggests that the “science of life” hasn’t done a very good job of keeping people alive. But if the Indians see it differently and want to rely on “ancient wisdom” instead of on modern science-based medicine, it’s their funeral (sometimes literally!). Deepak Chopra is the most prominent proponent of Ayurveda in the United States. He was trained in India; in my opinion, America would have been better off if he had stayed there.”For me Deepak Chopra practice is more like a cult with Ayurveda front.
Sometimes modern drugs are prescribed together with herbal remedies for symptom relief aids.
It’s true there’re weird homemade, no evidence-based, unregulated herbal regimens from fake doctor or real doctor turned herbal expert selling with high profits.
Perry said:This is the biggest problem with ancient ideas like Ayurveda or TCM. They are a belief system, they are not a system of reliable knowledge. They have no way of discarding bad ideas like Bloodletter (which is a feature of Ayurveda).If NIH would look into Indian and Chinese studies rather than relying on only American studies, there might be somethings other than just a belief. I humbly believe working together will take us further than working alone but I doubt I will see it in my life time.
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Dreamer77 said:
I’m skeptical this was the work of your cream alone with no laser treatment involved since there’re HIP, HIE lesions and boy what a poor stiching.
Dreamer77 said:
Back to the original post formula, Wasn’t there an Australian brand put a product that create similar effect to this out around 10-15 years ago?
It comes in white/purple tube, anyone remember the name?
So you are not the first one.
It’s been a long time since I heard the name Oil of Olay. -
Abdullah said:What is this expensive cream used for?
Some brands range from $500 - $1,800.
Dreamer77 said:The formula drastically reduces all wrinkles and expression lines throughout the entire face right from the first application after 5-10 minutes from 1st application to be more exact.
Are you interested in letting go of the formula and IP with full range tests from Intertek and clinical trial subjects 200 for $13.3M(negotiable)?
Or if you are a professional formulator with GMP certified facility, how about $33.31M + annual MCQ production contract?But maybe fix the stability issue first.
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The least I have paid for IP is 10,000.
Ask for more 5,000 - 7,500. -
high speed
add a lil xanthan
add Hydrogenated polyisobutene a bit
drop diol a bit
or sub NaCl with Magnesium Sulfate
should be ok around 1 month or sopure KAPPAPHYCUS ALVAREZII EXTRACT 2? or KIRIBIRTH BG 2?
why w/o?
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Clinique used to have cyclomethicone in their old repairwear night cream but the new one doesn’t have it.
Graillotion said:Night creams are in my understanding… thicker, more dense, a richer feel.Depends on your market - Korean brands tend to keep it very lightweight but have to be dewy for some period of time.
some use it
i.e. 100+ USD night cream - Which brand? Yeah that brand.
Aqua/water/eau, glycerin, propanediol, squalane, cyclopentasiloxane, triethylhexanoin, panax ginseng root extract, origanum majorana leaf extract, ziziphus jujuba fruit extract, thymus serpyllum extract, royal jelly extract, stearyl glycyrrhetinate, camellia sinensis leaf extract, algae extract, scutellaria baicalensis root extract, oryza sativa (rice) germ oil, camellia japonica seed oil, sericin, inositol, glyceryl stearate se, polyglyceryl-2 diisostearate, ppg-5-ceteth-10 phosphate, sodium lauroyl lactylate, sorbitan stearate, trideceth-12, ethylhexylglycerin, peg-240/hdi copolymer bis-decyltetradeceth-20 ether, butylene glycol, behenyl alcohol, parfum/fragrance, alcohol, phenoxyethanolLaneige
Water, Butylene Glycol, Cyclopentasiloxane, Glycerin, Cyclohexasiloxane, Trehalose, Sodium Hyaluronate, Oenothera Biennis (Evening Primrose) Root Extract, Prunus Armeniaca (Apricot) Fruit Extract, Beta-Glucan, Chenopodium Quinoa Seed Extract, Ascorbyl Glucoside, Magnesium Sulfate, Zinc Sulfate, Manganese Sulfate, Calcium Chloride, Potassium Alginate, Ammonium Acryloyldimethyltaurate / VP Copolymer, Polysorbate 20, Dimethicone, Dimethiconol, Dimethicone / Vinyl Dimethicone Crosspolymer, Propanediol, Ethylhexylglycerin, Stearyl Behenate, Polyglyceryl-3 Methylglucose Distearate, Hydroxypropyl Bispalmitamide MEA, Inulin Lauryl Carbamate, Alcohol, 1,2-Hexanediol, Caprylyl Glycol, Carbomer, Tromethamine, Disodium EDTA, Phenoxyethanol, Fragrance, Blue 1 (Ci 42090).Huxley Fresh
Opuntia Ficus-Indica Stem Extract, Butylene Glycol, Dimethicone, Cyclopentasiloxane, Water Glycerin, Glycereth-26, Cyclohexasiloxane, Trisiloxane, 1,2-Hexanediol, Cetyl Ethylhexanoate, Opuntia Ficus-Indica Seed Oil, Ceramide NP (Ceramide 3), Phyllostachis Bambusoides Juice, Betula Platyphylla Japonica Juice, Portulaca Oleracea Extract, Acorus Gramineus Root/Stem Extract, Citrus Grandis (Grapefruit) Seed Extract, Perilla Frutescens Leaf Extract, Beta-Glucan, Sodium Hyaluronate, Hydrolyzed Jojoba Esters, Dimethiconol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Polysorbate 20, Polysorbate 60, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Carbomer, Propanediol, PEG-40 Stearate, Palmitic Acid, Ethylhexylglycerin, Stearic Acid, Alcohol, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Polysorbate 80, Potassium Hydroxide, Disodium EDTA, Phenoxyethanol, Fragrance.Huxley have thicker and richer texture too.
and Huxley sleep mask
OPUNTIA FICUS-INDICA STEM EXTRACT, GLYCERIN, BUTYLENEGLYCOL, CYCLOPENTASILOXANE, CYCLOHEXASILOXANE, TREHALOSE, AQUA/WATER/EAU, 1.2-HEXANEDIOL, OPUNTIA FICUS-INDICA SEED OIL, CERAMIDE NP(CERAMIDE 3), SODIUM HYALURONATE, BETA-GLUCAN, CENTELLA ASIATICA LEAF EXTRACT, PERILLA OCYMOIDES LEAF EXTRACT, PAEONIA SUFFRUTICOSA ROOT EXTRACT, SALVIA OFFICINALIS (SAGE) LEAF EXTRACT, CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT, ACORUS GRAMINEUS ROOT/STEAM EXTRACT, PERILLA FRUTESCENS LEAF EXTRACT, THEOBROMA CACAO (COCOA) EXTRACT, HYDROGENATED LECITHIN, AMMONIUM ACRYLOYLDIMETHYTAURATE/VP COPOLYMER, POLYSORBATE 20, DIMETHICONE, DIMETHICONOL, CARBOMER, DIMETHICONE/VINYL DIMETHICONE CROSSPOLYMER, PROPANEDIOL, ETHYLHEXYGLYCERIN, ALCOHOL, DEXTRIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, CETYL ETHYLHEXANOATE, POLYSORBATE 80, TROMETHAMINE, DISODIUM EDTA, PHENOXYETHANOL, PARFUM/FRAGRANCE, BENZYL SALICYLATE, HEXYL CINNAMAL, CITRONELLOL.If I remember correctly, you have an in-house influencer right? She definitely have more insight than me.
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Xanthan 0.7 is quite high (for my taste), it forms a film and tighten the skin.
I had issue with pullulan with low humectant.
Maybe adding some glycerol would help or sub it with 940. -
I wouldn’t recon Cosmoperine® for amateur (sorry if you are a professional).
DMI and Ethoxydiglycol - will do. EU restricts Ethoxydiglycol % tho.
Specific type HA is used as dermal filler, US FDA approved it thousand years ago? I can’t remember.
https://www.fda.gov/medical-devices/aesthetic-cosmetic-devices/fda-approved-dermal-fillers