[Pattsi]

I personally don’t concern about efficacy. There will be 2 more hitting the US market soon. Make sure you monitor yourself. 

But this

An interchangeable biosimilar product may be substituted for the reference product without the intervention of the prescriber. The substitution may occur at the pharmacy, a practice commonly called “pharmacy-level substitution”—much like how generic drugs are substituted for brand name drugs, subject to state pharmacy laws, which vary by state.

If I were the prescriber, I would like to be notified before interchange.

From outsider POV, you should have passed universal health care. 

[Pattsi]

@Fekher - I’m not Arabic, only know basic bits and bobs of Arabic.
I think I saw it in Jeddah, made in Jordan but the jar was green.
If it’s from China, there’s a high chance that LOI is inaccurately listed.  

[Pattsi]

Fekher said:

@ketchito have you an explanation why in shampoo, carbomer can increase the viscosity however in hand gel the opposite?

Now I’m curious, is this product possibly made in Amman? How can they use نشاط إعادة توليد الخلايا on the label.

[Pattsi]

Welcome to the forum.

To get more answers accurately, you may have to provide more information.

Such as your formula, what is the problem you have, … etc. 
 

[Pattsi]

I had this one (still have) under different name before I bought IKA.

https://m.vevor.ca/magnetic-stirrer-c_11062/20l-digital-overhead-lab-stirrer-mixer-speed-adjustable-2000rpm-p_010434825593

It’s not top quality but useable.

Now it has rust at the neck where you attach the blade’s shaft, maybe I didn’t do maintaining well.

Not sure about capacity - Maximum I have made is only 1 kg low viscosity body wash.

Note - I am only at DIY level, mostly testing fragrance, gel, serum, body wash, rarely make emulsion. 

[Pattsi]

@MarkBroussard - good point, it doesn’t have to be peptide, it would be better if the claim ingredient is in line with the whole series you want to promote, jumping your own brand may not be a good idea. Unless you are strong enough to have a stand alone functional eye cream, adding peptide as a star dust wouldn’t hurt.  

[Pattsi]

Website is a must, email marketing still works well.

Younger audiences prefer Tik Tok.
Instagram doesn’t really generate much sale but you have to be there.
Facebook and Google for older audiences.

Ideally, you would have to be present in all platforms.
But if advertizing fund is limited, you have to identify your audiences first and you will have general idea how to be present to them.

And many more strategies marketers use.

MarkBroussard said:

@Waterbliss

Why does a 5 / 5 star rated product have a “very thin profit margin” … I would address that issue first.

Agreed. Will it worth advertizing?

But first and foremost, have your identified your brand?  

[Pattsi]

Graillotion said:

So, the question.  Have any of the peptides actually gotten to the point where very respected individuals firmly believe they have a significant value? 

None except for one that’s used in eye lash serum, somehow it seems to work(?) a little.

Graillotion said:

However, as I speak to some respected marketing type folks, they are rather adamant that my new eye cream will need a peptide.  I guess I should have clarified…maybe they said ‘needs’, they were referring to claim and marketing value, but from the gist of their recommendations, I think they fully believed in the performance of peptides.

I would say, throw in at least 3 peptides or use a blend or two, the more the fancier. And maybe some amino acids or those plant stem cell short peptides.

From my humble experience, only 3 ingredients have been proven to be working well for eye cream, 1) luxurious packaging 2) superb texture and 3) advertizing.
And maybe retinol and its derivatives.

Cheers and good luck on your project.

[Pattsi]

From the original post context, the brand is UK based, also have bricks and mortar stores model, it’d likely be bigger than micro-sized brand. So I presumed it was hundreds or thousands up pieces.

The manager might want to see or feel how it look, and so he/she requested 1 piece before proceeding with the plan. It would be lab scale production 100-300 g but only fill a 5 g container, not a 5 g production.

If it was only a 5 g piece for only 1 store, I also find it ridiculous.

Perry said:

but we are a marketing run industry. These types of things happen to chemists all the time. At my company about once a quarter someone in R&D had to make a special blend of an aftershave product that we didn’t sell but the company owner loved to use. It had to be made exactly the same way every time following a procedure developed in the 1960’s. I just remember having to cold filter the blend to remove some haziness. It took a lot of time & was not part of the regular job responsibilities. But when the owner wants something, you do it.

I have heard. I have never done that, I’m having fun learning and making it myself.

@CoaJuniorFormulator - Cheer up, life is ahead. You will face weird marketer(s) like me(?) at some point. 

[Pattsi]

… How come it was a weird request.
I ask the production team to make sample-sized giveaway all the time.

CoaJuniorFormulator said:

painfully busy. The paperwork alone… 

I’m quite speechless. Are you a kid on assignment? Did they abuse your working hour?

CoaJuniorFormulator said:

present as a sample to the general public at one of our bricks and mortar stores ????‍♀️. 

In person experience is powerful for new product launch and if that potential customers get a little gift to take home, that’s a plus.  

If my request were to be declined, I would like to hear a proper reason.

But well I’m not in the production team so you have to wait for other members’ thoughts.

[Pattsi]

Common - anti-wrinkles, puffiness, dark circles under the eyes.

Graillotion said:

***  Does the consumer expect an eye cream…to have lightening properties? ***

They do want to get rid of dark circles under the eyes, skin lightening ingredients will certainly help them appear lighter but not completely gone as the pathology is different from pigmentation.

Coffee extract or caffeine is good for claim but might be too common.

In my humble experience, greatest sale eye cream is the one with blur effect + super long lists LOI.

Eye cream is one of the most expensive and also one of the most useless of all.

[Pattsi]

@Padmavathi - Thank you Padmavathi, my marketing brain is blinking again.

Pharma said:

 he/she tries to sound smarter than you but both know what’s really going on. 

@Pharma - It’s funny that it happens everywhere I guess, there always will be some doc trying to act like they know more than pharmacists, in my humble life, there’s only one time that I had to correct an intern pharmacist but he’s sooooo (with million o) cocky, wanted to show off in front of a pretty intern and forced two completely messed up drugs on me, so I had to call for his supervisor. - well this is too off topic sorry.

[Pattsi]

@Padmavathi - Thank you for AYUSH information, I didn’t know it is also cover personal care, I thought it only licensed to pharmaceutical manufacturer.

May I trouble you with one question, can personal care under AYUSH license be sold across states?

@Pharma - Good thing they are changing but I’m curious how will you write prescription, Neomycin 3.5 mg cream w/ aaaaa, bbbbb, ccccc, dddd, not w/ xxxxx, yyyyy, zzzzz, that one, Ah Ahr not that one, yeah that one, like this? Sorry, just try to be funny.  

[Pattsi]

Ariel P&G - liquid detergent - If I’m not mistaken, Indian regulation for powder and liquid detergent use the word active ingredients “should” be listed in declining order of inclusion. So they left out LOI as so other big brands in India. (may have to wait for members from India to clarify this again)
But their versions for other countries have listed active ingredients.

As for BIOTIQUE, they simply violate the rule. You should look for a good example not a bad one, Himalaya is doing great with proper product, isn’t it.

MarkBroussard said:

Graillotion said:

You are aware of the 1% rule?  

Personally, I would like to see the 1% rule done away with and you just list all ingredients in declining order of inclusion.

@MarkBroussard  - I have to disagree with you on this. How do we supposed to list our star dusts then lol. 

Mayday said:

It’s up to the Indian authorities to enforce their own regulations, and what they are doing now is what they can get away with in their regulatory environment.

[1]: If you want to be scared to ever again take generic drugs, listen to this podcast episode about Ranbaxy’s fraud in the pharmaceutical industry. If blatant fraud was occurring on this scale in pharma, I expect the Indian cosmetics industry would be worse. No offense intended to those individuals and companies in India who produce safe, high-quality products, and do not engage in such fraudulent practices.

From my humble experience, when dealing with Indian counterpart, if you are a newbie, it might be safer to go through government representatives or trusted third party organizations. With all respects, India is the land full of opportunities but also full of fraudulences.

[Pattsi]

Xanthan gum 2%  - would be very sticky like a glue and flaky on drying.
Is this gel meant for black girls? I’m not sure it will perform well. 
You may need to change to polymer.
Or if you want it natural, you have to wait for more experienced members.

[Pattsi]

I’m not a formulator but from your list, it seems you are a bit low on emulsifier, you have to try what ratio work best for your formula and might consider preservative as well.
Lets wait for experienced members advices.

[Pattsi]

PG - 22
Glycerin - 32

I’m not sure, my brain is in a blur now, isn’t this water-based lube patented somewhere?

[Pattsi]

MarkBroussard said:

@Graillotion

The best way is to identify is the International Convention:  Simmondsia Chinensis (Jojoba) Seed Oil

We did as Mark said and never had problem anywhere, US included. 

[Pattsi]

Lovely picture.

Those flowers would make good tempura topping for your ramen.

[Pattsi]

Flow chart summary.

https://cdsco.gov.in/opencms/export/sites/CDSCO_WEB/Pdf-documents/New-Drugs/Process/NDD_APPL_Organogram.pdf

You can contact your local state authority if your formula requires clinical trial or not. 

[Pattsi]

Thank you @PhilGeis, very important course.

[Pattsi]

Had similar problem wanting to reduce cost by switching to mineral oil, the cooling lasted only few seconds (menthol at 1%), now switched back to veggie oil.
o/w cream was formulated and the cooling effect was better than oil based but it wasn’t perceived well by tested consumer group so it wasn’t put on sale. 

[Pattsi]

GeorgeBenson said:

Indeed, Lotioncrafter and MakingCosmetics both say to keep it around 6. I’m glad to know I am free to formulate my ph down low where I want it. Someone should probably notify them of this error….I would tell them but not sure they’d take my word for it ????

Doesn’t one of them (or both) issue their own SDS?
Are they capable of doing so?

[Pattsi]

https://sensient-beauty.com/pigments-and-pearls/

https://www.youtube.com/watch?v=ecZm9begSG8

[Pattsi]

Graillotion said:

Oh…and this is an ‘all over’ deo (use anywhere).  I have seen some of the major Indie brands really get ‘torn into’…when they mention private areas.

What is some elegant language for that concept?   

“privates” or “intimates” areas, most physicians’ advices, you shouldn’t put deo on your junkoes or junkies. If they mentioned it, they were asking for it. 

Take a quick look 

https://corpusnaturals.com/products/no-green

https://taosaer.com/pages/about

Quite beautiful, a bit feigned, a bit unrelatable. 

You can also do “Premium” and emphasize on natural actives as a tie-in with your personal experience.

I assumed your end price might be on the higher edge than mass products and that would likely makes your potential targeted consumer group is of very well informed (or very well mis-informed), so you may have to choose your wording wisely.

Specify your target and you will have the general idea of what they are looking for, and market your product accordingly.