Microformulation
Forum Replies Created
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Hair Growth is an OTC Product. While there may be anecdotal claims on the individual ingredients, it would be an unapproved drug. As many will counter with, “but it works”, that is still not acceptable to the FDA.
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Also, I may be wrong, but in the Regulatory courses I have attended, the word “and” is generally not used in a properly written INCI Deck.
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What does it say in the relevant section of the MSDS? In some cases, this will give you a range. Not always but worth a shot.
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No, not unless you have the testing and documentation for the “standard” and testing for each individual lot (batch produced). Buyers can and will ask for these documents. They ensure consistency and safety in botanicals for example. Your “glycerites” are untested. The testing can be costly. Just buy standardized ingredients.
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What are your issues with Tocopherol or Rosemary?
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Buy some texts or take a course like Perry’s. Don’t use place a great deal of weight on online citations.
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Tocopheryl Acetate will NOT protect your Formulation from oxidation. Again. these are some pretty broad and rudimentary subjects that one should explore on one’s own through credible (not online most likely) sources. Feed a man, teach them to fish and all that…
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You are essentially asking for a full Formulation which is work product.
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Nobody uses 10:1 dilutions for pH testing except under some very rare conditions.
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I don’t recall, but when we needed to know we accessed an old patent. *Scar Products” I ‘believe” it was the 200 cst or higher.
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I have to skirt NDA’s, but in general terms at no level of EDTA did we see any change in the foam properties when compared to a control. They did consumer testing and the reviewers noted no real change in performance. I believe afterward they went forward but expanded the concept to “shampoos custom made.” I would suppose it might be more significant with a saponified soap-based shampoo such as a Castille Soap.
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I worked on a project just like this in the past. A company wanted to test people’s water for hardness and then “customize” a shampoo/conditioner product for the client. In testing, however, it showed no real significant benefit at all levels. The takeaway was that water hardness was much less significant with syndets than with traditional saponified soaps.
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Rockstargirl said:Yes good points. I agree it is good for optics (and knowledge!) is each certification equal? Is there a certain institution you would like to see certificates from?
I haven’t sourced out a provider in about 4 years since I don’t work with manufacturers internally very often anymore, hence no need for the service. Back then I called a Colleague who specializes in Cosmetic Regulatory and asked for some sources.
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Amazon and some e-commerce sites will ask for a letter from a Third Party affirming that your manufacturer is cGMP Certified. My more savvy clients demand it when we source manufacturing.The new Cosmetics Law that is being introduced would make cGMP mandatory.In the end for a client, when they see GMP Certification, they expect a consistent and safe product.
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@Pharma “Some EOs have medicinal properties pretty much like ‘chemical’
pharmaceuticals and ‘drugs’. Unlike many standard drugs, they don’t have
one defined molecular target and one scientifically proven mode of
action. But neither do Aspirin and Tylenol.”Way back in 1984 when I attended Pharmacy School, they sure made us learn the mechanisms of action for these two drugs. -
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The Essential Oil theoretically “could” work wonders. However, as far as drug claims go, you can’t make a single one based upon these uses, at least in the US.
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1. Proper nomenclature should be in wt/wt%. That is the proper notation.2. All raw materials must be weighed.
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“..a couple of drops of Vitamin E”Are you mixing your ingredients by weight?
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MarkBroussard said:Microformulation said:I think a better list would be the Formulations that people requested, but which were not feasible upon proof of concept.
Oh yes! … the “I’ve never seen a product like this before” and when they describe their concept to you it violates the laws of chemistry and physics. I can’t recall any specifics, but certainly have had a few of those.
1. I had a client that was “over top natural” and wanted to create a Pomade that was all butters and oils, BUT would change color. “Can’t we just use the same chemicals as pH strips?”2. An intimate area hair removal product that would have used a high viscosity (think silly putty) silicone which would be applied to the area and the hair pulled away. A polymer chemist had already told them it was not possible. -
I think a better list would be the Formulations that people requested, but which were not feasible upon proof of concept.
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You need to look at the GRADES of SS used or research attentuation. With these measures, it is really a non-issue for the most part.
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“90 percent of what you put on your skin is absorbed into the body.” It is then usually used as the Foundation for a campaign of chemophobia.
