Forum Replies Created

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  • VitalikButerin

    Member
    December 18, 2020 at 10:30 pm in reply to: Cost Effective Testing Lab in UK
  • VitalikButerin

    Member
    December 18, 2020 at 2:23 pm in reply to: Cost Effective Testing Lab in UK

    @Bill_Toge do you know whether a chemist is required to write out a toxicology report? Or can data from a microbiology test be used 

    FYI here’s a decent lab: Oxford Biosciences offers cosmetic product challenge testing for £150 per product.  The tests are commonly referred to as Microbial Challenge Test (Challenge) and Preservative Efficacy Test (PET) but they are the same test.

    https://oxfordbiosciences.com/testing/

  • Hi mate 

    Not bad price for a lab homogenizer, search on eBay too 

  • VitalikButerin

    Member
    January 16, 2020 at 4:41 pm in reply to: Can you tell the price of these ingredients?

    yes such large companies have exclusive distributors 

  • VitalikButerin

    Member
    January 16, 2020 at 4:38 pm in reply to: Scales for business

    for a home business any reputable scale should be fine they give the +/- on the scale. business is expected to be 4% within the given range.

    many people use chinese lab scales which work fine for them too. 

  • VitalikButerin

    Member
    January 15, 2020 at 2:11 am in reply to: Oh Boy! Big mistake?

    Is there a chance the client finds out? If so how? 

    Also formulas unless are really unique are not that special 

  • VitalikButerin

    Member
    January 5, 2020 at 11:35 pm in reply to: High Shear Mixer

    Dtdang said:

    I have question:
    1) all ingredients that are water soluble are mixed well with stirrer
    2) all ingredients that are oil soluble are mixed well with stirrer.

     Now 1) and 2) are put together for emulsion 
    Question: should I use stirrer or homogenizer?

    thanks in advance 

    Homogenizer of course 

  • VitalikButerin

    Member
    January 3, 2020 at 3:18 pm in reply to: High Shear Mixer

    Stirrer just stirs. 

    Homogenizers like emulsifyers aim to combine the two difference molecules into one mixture. Like powders and oils, it really breaks them down a lot more whilst spinning them, not only just by stirring them 

  • VitalikButerin

    Member
    January 2, 2020 at 9:26 am in reply to: High Shear Mixer

    Dtdang said:

    Southwest science has sos20 digital mixer costs 390 usd but it can handle up to 20 liters and the shaft diameter from 0.02 to 0.375 inch

    that’s just a stirrer and not a homogenizer - i would rather DIY a stirrer 

  • VitalikButerin

    Member
    December 29, 2019 at 3:12 pm in reply to: High Shear Mixer

    How many watts should a decent lab mixer have? 

    2980 rpm 

    Depends on how many liters you want to mix 

  • VitalikButerin

    Member
    December 22, 2019 at 11:51 am in reply to: Polidocanol

    Hi belassi 

    I actually found a number of suppliers, I can probably send it to you. 

    Please inbox me 

  • VitalikButerin

    Member
    December 22, 2019 at 11:45 am in reply to: Polidocanol

    Hi belassi,

    This is because it is a drug, I doubt you can use it in formulas

  • VitalikButerin

    Member
    December 22, 2019 at 11:34 am in reply to: New lab

    My advice is, if you buy machinery from China make sure you understand how the machine works to know how to fix it 

    Also you don’t always have to go expensive, the best is to go simple

  • VitalikButerin

    Member
    December 22, 2019 at 9:59 am in reply to: Supplier for Hexanediol/Pentanediol request

    If you have a company set up, it’s not hard to request samples. 

    You shouldn’t expect any credit though so everything you’d have to pay for up front of they request money - on samples not sure if they give 1 litre maybe 100ml 

  • VitalikButerin

    Member
    December 22, 2019 at 9:55 am in reply to: AliBaba conundrum

    In truth, you need to audit the supplier from AliBaba first 

    They can send you anything and you won’t be able to verify it 

  • VitalikButerin

    Member
    December 21, 2019 at 11:06 pm in reply to: High Shear Mixer

    There are auction websites, Ive even seen silverson second hand with all the parts for £800

    I understand this is not homogenizer, but this is a used auction website ; but let me tell you, eBay auctions are always cheaper! 

    https://www.equipnet.com/ika-rw-20-digital-lab-mixer-listid-609987/

  • VitalikButerin

    Member
    December 21, 2019 at 10:56 pm in reply to: High Shear Mixer

    That’s very expensive £600 you can buy second hand one for that price of   good brand 

    I’m guessing this is a lab one?

  • How much 

  • VitalikButerin

    Member
    October 11, 2019 at 3:58 pm in reply to: different use of homogenizer working head

    The rotor/stator head on the left most closely matches the industrial scale units we have in general use. Silverson carries different shear-head combos for these. Missing from this thread is scale-up speed. Virtually all powered industrial homogenizers run at 3500 rpm, and that is with a 15hp/460V/3phase motor. A scant few may go to 6000 rpm. I’ve had to school many a bench chemist on this when they say “Wheee, look how well it worked at 15,000 rpm!” If you cannot scale-up then why bother unless it is for home use?

    Do you use Chinese made ones or silverson ones? 

  • VitalikButerin

    Member
    October 10, 2019 at 11:02 pm in reply to: Silverson Homogenizer vs Chinese eBay homogenizer

    Anyone? 

  • VitalikButerin

    Member
    October 10, 2019 at 6:08 pm in reply to: different use of homogenizer working head

    @angelz:

    I use both of these types of homogenizers.  The homogenizer on the right is really good for making small samples … 300 grams or so.  But, I had to have a machinist build a custom “emulsification cage” for it because that homogenizer head, as designed, pulls lots of air into your emulsions.
    So, basically, I had a machinist make a “Silverson Workhead” with an emulsor screen (just like the homogenizer on the left) that fit onto the homogenizer on the right.  Solved the problem.

    How much did this cost to reverse engineer,? 

  • VitalikButerin

    Member
    October 10, 2019 at 12:09 pm in reply to: GMP training

    Find a manual and follow it 

  • VitalikButerin

    Member
    October 7, 2019 at 7:09 pm in reply to: Silverson Homogenizer vs Chinese eBay homogenizer

    Herbnerd said:

    You have to be sure of the company before buying - it really is buyer beware in China unless you have someone on the ground who knows what they are doing and the best companies to deal with. There is rarely any come back if there is a problem.

    A company I worked for bought an in-line homogeniser for light work (incorporationg aloe powder into water), in which there was a hopper to pour the powder into. It didn’t do the job. The only way they could get it to work was to put another pump in-line to pump the liquid through the homogeniser first - which defeated the point of buying one in the first place.

    The other thing to watch out for is the bolts - they tend to be mild steel and will shear off quickly. Best thing to do is replace all bolts beofre you start using it.

    Thankyou for that, but I’m interested in the basic homogenizer, for example: 
    https://rover.ebay.com/rover/0/0/0?mpre=https%3A%2F%2Fwww.ebay.co.uk%2Fulk%2Fitm%2F382053593170

    Ebay /paypal should gurantee.. 

    However I’m wondering if they’re good enough to make creams? 

  • VitalikButerin

    Member
    May 20, 2019 at 9:54 pm in reply to: UK regulations… Do you need a chief chemist?

    @Perry  thanks

    @Bill_Toge  Do you offer this service ?

  • VitalikButerin

    Member
    May 3, 2019 at 10:22 pm in reply to: HELP! Domain / brand infringement
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