PhilGeis
Forum Replies Created
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ariepfadli said:Try with formaldehyde releaser such DMDM Hydantoin, imidazolidinyl urea, etc. They effective and safe for rinse off productsGood ones above but recommend as best Na benzoate/chloromethyl isothiazolinone /EDTA.
However these are manufacturing contaminants - appears you need major improvement in manufacturing hygiene and GMP’s. Preservatives are largely intended to protect during consumer use. -
Are you in US ?
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Abdullah pointed out you have a system. Be aware, for wipes you must challenge test the wet wipes - not just the fluid.
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No one sterilizes and you don’t need sterility. You probably don’t need to use any - are the bottles clean?
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Not sure there is a limit or at that level concern is more potential than reality.
Yup 35% by weight. -
Sodium phytate is a good chelator. Stay with it.
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Graillotion said:I never read the label on my distilled water before tonight. Is says:
Processed by: Steam distillation, microfiltration, ozonation.So is that the trifecta….as good as I could hope for from a big box store purchase, @PhilGeis ?
Ozonation helps., it’s typically used for bottled water. Go with the test
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Pharma - and worse - the damned things are so hard to culture, it takes forever to figure out the problem (discolor, clouding, slime) is microbial.
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Moderate halophiles can grow up to 20% salt and halophiles are among the contaminants of many household and industrial products - minerals/salts themselves are often the source.
Pharma makes a good point - they are heat sensitive. Boil it and seal it - or take your chances. -
20% is not prohibitive to microbial growth.
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That means very little - it’s a poor preservative
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Leucidal is not a very effective preservative.
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Just use the paddle media every time you formulate. These are very poor for products but not so poor with water.
Decide upfront what result will cause you to toss the product you made. -
Mine is industrial experience - recirculating water systems with ozone and heat. Maybe contact the manufacturer - they might be ozonating.
Preservatives are intended to protect consumers in use - not correct for poor GMP’s. Even a “good” preservative system can be overwhelmed. Our systems are weak - not accomplishing in a month what a disinfectant does in 10 minutes or less. They have to be weak or they’d not be safe in use.
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Microbial content of water is dynamic. Cepacia, ~ the most common cause of recall, can grow to millions in a day in distilled water. Water is the most problematic ingredients - you don’t know micro quality at formulation until days after the product is made and packaged.
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If the peptides are actually synthesized by the plant - https://pubmed.ncbi.nlm.nih.gov/23252967/.
Why are you using it if it causes such angst?
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Wet wipes have no rinsing step like shampoos - so are leave on.
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For antimicrobial efficacy in wash?
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Think phenoxy is not needed with DMDM Hydantoin and Parabens - the classic combination is a formaldehyde releaser and parabens but add EDTA.,
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MIT as supplied with CMIT at total ~5ppm in rinse off products is safe in use and continues to be primary in that context.
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Any observation for 40C? 50C is pretty high.
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Doubt it pharma - lauric might but the longer chain fatty acids do not and would more likely undergo beta oxidation as substrate for the pseudomonads.
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Don’t waste your money on either - supplier marketing hype. Efficacy would be phenoxyethanol.
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Both are wrong.
Where effective Phenoxyethanol is usually fine at 5000 ppm and the other two are pretty useless in any application. Pseudomonads have plenty of esterases. -
Are you in US?