Home Cosmetic Science Talk Formulating CHLORHEXIDINE digluconate 7.1% equivalent to 4% chlorhexidine

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  • CHLORHEXIDINE digluconate 7.1% equivalent to 4% chlorhexidine

    Posted by Raychemist on September 16, 2021 at 3:21 pm

    I have been wondering about 7.1% Chlorhexidine digluconate being equivalent to 4% chlorhexidine.

    Can someone help me to understand the above statement and what the possible formula might be?

    Thank you in Advance

    Raychemist replied 2 years, 10 months ago 2 Members · 2 Replies
  • 2 Replies
  • PhilGeis

    Member
    September 16, 2021 at 3:44 pm

    Chlorhexidine digluconate salt MW is 898 of which Chlorhexidine  molecule @MW 505  is ~56% of the salt.  56% of 7.1 = 4.
    The salt enhances solubility.

  • Raychemist

    Member
    September 17, 2021 at 12:18 pm

    Thank you . most appreciative

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