• Formulating

  CHLORHEXIDINE digluconate 7.1% equivalent to 4% chlorhexidine

  Posted by Raychemist on September 16, 2021 at 3:21 pm

  I have been wondering about 7.1% Chlorhexidine digluconate being equivalent to 4% chlorhexidine.

  Can someone help me to understand the above statement and what the possible formula might be?

  Thank you in Advance

  Raychemist replied 2 years, 7 months ago 2 Members · 2 Replies

  • formulating
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• 

  PhilGeis

  Member

  September 16, 2021 at 3:44 pm

  Chlorhexidine digluconate salt MW is 898 of which Chlorhexidine  molecule @MW 505  is ~56% of the salt.  56% of 7.1 = 4.
  The salt enhances solubility.

• 

  Raychemist

  Member

  September 17, 2021 at 12:18 pm

  Thank you . most appreciative

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