PhilGeis
Forum Replies Created
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shoot for 1000 ppm as acid
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None is cheap and an iron system is pretty poor for water storage or much else. Between biofilm and water and micro-based corrosion, think its not going to serve well.
EDTA would make it worse and ozone is out of the question.Stainless (316) will be more costly now but less in long term
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Think major cosmetic guys largely do their own contractor audits. Whoever you use, suggest your specific auditor should have major company background.
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and reduce the benzoate to ~3000 ppm
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Water is a primary source of contamination in cosmetic manufacturing. Stored, in whatever tank, vessel, bugs will grow and perpetuate themselves in biofilm. You’ll need some mechanism to control that problem and that typically involves a recirculating systems - the optimal systems is preserved with as constant heated water or ozone treated. Some use UV light and a micro filter recirculating through a storage tank with periodic sanitization of the system.
Hope you/ve stainless steel rather than PVC. -
Do not store water.
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5ppm with EDTA
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Agree re Germall + and add EDTA - you could also use Kathon/Na benzoate/EDTA
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Good luck then. Maybe be same wholesaler but different producers.
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Did you get a coa?
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Na benzoate is not enough. You could add chloromethylisothiazolinone as do many of the major marketers.
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Benzoate by itself is not a good preservative - esp. in a shampoo.
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Wonder at Na benzoate by itself as adequate preservative for a shampoo.
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Thanks!
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@ngarayeva001 - could you specify the class of preservatives?
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Here’s protocol of the type major companies use — https://cosmeticseurope.eu/files/5914/6407/8121/Guidelines_on_Stability_Testing_of_Cosmetics_CE-CTFA_-_2004.pdf
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@chemicalmatt
Much as I think these are gimmicks for cosmetic testing, also know you’re solid in your work. Can you describe your application? -
There are no controls per se - but you might compare a major product at increasing dilution (100%, 50%, 30%) to get a feel for the test and generate differential data.
Shampoo probably since it will go into solution. -
Here’s USP 51 as Matt mentioned. http://www.uspbpep.com/usp29/v29240/usp29nf24s0_c51.html
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Water is prob ok - product not so sure.
Undiluted product would be the worst. Assume you’ve diluted product. Would have to satisfy suitability for each product. In that context might be ok for some - but even there, question the volume actually exposed. -
Have you been trained in aseptic technique?
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Prob should have a consistent protocol and you should sanitize after washing/cleaning. Shouldn’t offer bugs an opportunity to grow anywhere - or corrosion if that’s what this stuff is.
The black dots were in 3 day old product residue left in hopper vessel? Can you check retains?
Hypochlorite pH should be ~6.5-7 but NOT less than 6.
Culture a few of those black dots. Even if a fungus, doubtful it’s Aspergillus brasiliensis. -
Not normal - visit the shelves and squeeze some of the major brands.
Think you’re biggest risk in use for shampoos is water ingress in shower and dropped in bath. Wonder if those caps affect that dynamic.
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to Pharma’s point
Please demand chemical analysis as justification for the eye of newt, toe of frog “natural” preservative efficacy. Efficacy of most is based on internet rumor and supplier hype with comforting names of “Neodefend” and “Phytocide” for at best weak combinations. -
Air comes out when you squeeze with that design - it’s a poor closure.