

PhilGeis
Forum Replies Created
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Inactivation? Test it.
COSMOS/Ecocert confines your efforts to options limited in efficacy. Your package may limit consumer contamination but magnifies risk (via inhalation) if there is contamination. What is the quality of your production - water, raw materials, sanitization, etc.? Major manufacturers work on a 3 year product life.
To ketchito’s question - efficacy (hair growth and anti dandruff) - add safety, esp. via inhalation. How do you answer these?
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That’s a stretch - “soap” a single factor of product formulation - and maybe EO - is “hurdle. Suppose a bottle of chlorine bleach is hurdle.
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What’s your packaging?
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For shampoo - use isothiazolinone (as suggested), Na benzoate (2500 ppm) and EDTA (1000 ppm). Anionic surfactants raise the effective pKa for Benzoate.
Vs. isothiazolinone, Phenoxy is not as good but DMDM Hydantoin (2500 ppm) would be a replacement..
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I understand some may not be familiar with antimicrobial efficacy of benzoate/benzoic acid at near neutral pH. Here’s a ref - https://www.sofw.com/en/sofw-journal/articles-en/47-home-care/1703-enhancing-antimicrobial-efficacy-of-sodium-benzoate
and You’ll find it with isothiazolinones in many mass market shampoos.
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In concept, preservation by a combination of factors none of which has a primary antimicrobial effect - e.g. mildly acidic or basic pH, Aw <0.9, low % alcohol, etc. Maybe toss in a pump packaged.
Shampoos? Don’t bet on it. Don’t waste your time
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Your not in US?
Think your preservative system might need a little help for fungi and Gram positive bugs.
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PhilGeis
MemberMay 22, 2023 at 5:56 am in reply to: Gram + / Gram - / YMF…which category can one not afford to miss?Most frequent and most severe consequences - Gram negative bacteria - esp. Pseudomonas aeruginosa.
And, with cepacia, least likely to be controlled by nonconventional preservation
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still works for me - details from FDA Enforcement report
Nature Lake Foaming Hand Soap Tablets, Sea Mineral. 850 Fifth Street South, Hopkins, MN 5534
Class II - Hand soap has the potential to be contaminated with bacteria.
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PhilGeis
MemberMay 14, 2023 at 5:30 am in reply to: Is this preservative system enough for this amodimethicone conditioner?Probably
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PhilGeis
MemberMay 13, 2023 at 6:45 am in reply to: Help me make sense of this: effective and compatible over a pH range of 3 – 8.Aware of nothing for the natural “just stick this in” .
Can construct effective systems that meet “natural” contrivance based on formula and with chelator, glycol (at decent %’s), organic acid, if benzyl alcohol - with benzoic acid, phenoxy (not phenyl), pH control, process and package design. Rarely see evidence of this in most of the clean beauty offerings.
Sal acid has even been used as part but with very narrow, buffered pH range.
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PhilGeis
MemberMay 12, 2023 at 5:41 am in reply to: Help me make sense of this: effective and compatible over a pH range of 3 – 8.This is just marketing BS - slightly acid to 8 is cynical marketing at best showing profound ignorance of the objective.
Definitely weak vs Gram negative bacteria, again at any pH.
Do not use this stuff - build a system that should work in context of your product.
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PhilGeis
MemberMay 11, 2023 at 10:36 am in reply to: Is it ok to leave 100ppm hypochlorite in tank after sanitizationBut drain the tank af rinsing. Do not want a volume of any water sitting beyond 6-8 hours - growing bugs
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PhilGeis
MemberMay 11, 2023 at 8:53 am in reply to: Is it ok to leave 100ppm hypochlorite in tank after sanitizationHeat may not be cheap but works best.
You could use your process water - that offers no more risk than niormal making.
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That two terms are associated in a publication does not mean they report or confirm cause and effect. You might also research to meaning of endocrine disruption. The working definition (binding to estrogen receptors) would find many phytoestrogens such as are commonly found in diets profoundly more effective. Lastly - take anything authored by Darbre with caution - tho’ as a scientist you might enjoy her profoundly flawed methodologies.
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Amber doesn’t control evaporation - perhaps oxidation. and leaching.
For sprays, you should have a stronger system as, if present, contamination will be inhaled. Mere presence of a nonionic line Tween in formula does not mean it will neutralize but 221 is a weak preservative in any context. Perhaps phenoxyethanol?
What is pH?
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“Saponified oils” - it’s simply soap. “Hurdle ” here is pretentious.
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Not sure I’d call hurdle - reliance on soap formulation. Were there other factors?
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PhilGeis
MemberMay 29, 2023 at 2:16 am in reply to: Help me make sense of this: effective and compatible over a pH range of 3 – 8.Have a beer!
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Ever tested product after condumer use? What is your package?
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PhilGeis
MemberMay 29, 2023 at 1:20 am in reply to: Help me make sense of this: effective and compatible over a pH range of 3 – 8.Here’s the book https://drive.google.com/file/d/0B8A98zYzLCDRb2xadjU2MnlkQXM/view?resourcekey=0-VOuv7UH-bSJiN_jaQhb3Q\\
says “optimal activity” below 5, little above 8. That’s what I understand. My comment re benzoic acid with surfactants up to 7 is data based.
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Can you describe your hurdle technology? Is this in context of the soap base you mentioned before.
“In-use” as in the articles below. The major manufacturers put product in hands of consumers to confirm the basic efficacy of their systems . This has been shown generally conventional systems and would be esp important with hurdle. “Compliance” is rudimentary - gov folks know crap all about cosmetic microbiology and as I think you noted before -your guys did not ask for data.
https://academic.oup.com/jambio/article-abstract/128/2/598/6714996
https://journals.asm.org/doi/abs/10.1128/aem.53.8.1827-1832.1987
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PhilGeis
MemberMay 28, 2023 at 10:10 am in reply to: Help me make sense of this: effective and compatible over a pH range of 3 – 8.Gram + and fungi generally ~5 or less. Dave Steinberg liked it up to 7 - for me 7 and broader efficacy (some v. Gram neg) with benzoic acid in surfactants.
What is ref 16?
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Your soap solutions? Do you have in-use data?
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PhilGeis
MemberMay 23, 2023 at 6:16 am in reply to: Gram + / Gram - / YMF…which category can one not afford to miss?Yup - a bad one. Reminds of <b style=”background-color: var(-bb-content-background-color); font-family: inherit; font-size: inherit; color: var(-bb-body-text-color);”>Pseudomonas-induced corneal ulcers associated with contaminated eye mascaras. LA Wilson, DG Ahearn - American journal of ophthalmology, 1977.
also aeruginosa -