

PhilGeis
Forum Replies Created
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PhilGeis
MemberJanuary 24, 2024 at 5:36 am in reply to: Magnesium cream turning pink on the surfaceYou’ve a poorly-preserved turning pink. What are micro data?
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Doubt you’ll find a risk assessment and it’s a good bet youtubers never bothered.
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https://www.fda.gov/medical-devices/aesthetic-cosmetic-devices/microneedling-devices
fda.gov
The FDA has reviewed and legally authorized specific microneedling products as medical devices for use in specific areas of the body.
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Choice of supplier is sometimes forced by volume you want as some will not sell small volumes. Suggest you also consider Arxada. These guys have consolidate some of the older supplier houses - Dow MC, Lonza etc. and rather than just repackaging combinations are developing preservatives - real stuff, not natural eye of newt toe of frog BS.. Their phenoxy may not be special but their profits are investments.
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On what data are you claiming biodegradability?
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“Safe”?
pH - not at issue. Skin has no pH per se but techniques that propose to measure find it effectively buffered.
Fatty acids in soap - short chain are more biologically active - C12 may be more irritating on skin than longer chain.
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To your questions - cleaning what material and neutralization/eliminating what odor?
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That is a poor preservative system and a higher risk population is exposed. What is pH and packaging?
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That is a pretty weak preservative system - not much Gram neg protection.
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Was this changed supported by challenge by data?
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What size tank? Spray balls? What type of product residue?
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It’s associated with the addition of which preservative?
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Another poor preservative system. What are the micro data?
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PhilGeis
MemberJanuary 23, 2024 at 6:39 pm in reply to: Preservatives without Coconut and Palm (Allergy Reasons)Where are you with preservation?
As stated above phenoxyethanol is NOT coconut derived.
Benzyl alcohol and DHA is a poor preservative system and you’d be better off with Benzoic than Sorbic acid.
Leucidal is a WASTE.
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If using an alcohol - suggest phenoxyethyl rather than phenylethyl. Need to know pH before trying organic acid.
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Excellent article. I’ll add a chelator like EDTA you should be using to facilitate preservation should also be constraining potential production of benzene and it’s doubtful your pH is low enough to drive the reaction <3.
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Be aware - the product preservative will not have any efficacy in dilution.
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you do not need the plus.
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Agree - MIT/CMIT prob not appropriate. Can you describe packaging, process and anticipated consumer use?
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What is your country - regulatory climate? Methylisothiazolinone effectively banned in EU.
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Chelator is useful in preservation. Not sure its surface safety in your application.
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As in the microbial encountered in manufacturing - e.g. do you clean and sanitize equipment, control micro content of raw materials?
Rarely is one preservative enough. In this case, I anticipate the above will not be in control and application will bring water addition. If using only one - use the formaldehyde releaser.
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Should be ok. ~ 0.5% (5000 ppm) phenoxy and 0.3% Na benzoate.
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It’s not that great a system anyway. Why not try something more pedestrian like benzoate/phenoxy.
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Some of those are +/- garbage in any use and, if you’re in US, don’t think any are legal in your application. A formaldehyde releaser such as Sodium Hydroxymethyl glycinate with phenoxyethanol might work if your making is reasonably clean, BUT to be legal you need to find versions compliant to relevant biocidal/pesticide regs. - in US, registered as EPA pesticidal preservatives..