DRBOB@VERDIENT.BIZ
Forum Replies Created
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I don’t know of any reason it should?
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should be easy to run via HPLC at Tsub zero and after three months at 38C to provide 2 year shelf life.
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Try adding 1% dimethicone for rub in,
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What is criterion for stability and method?
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I don’t know as have never requested such but worth a try.It may be considerably more expensive but could generate specific mildness claims for that area but if you do it; get Dermatologist signature for only 350$ more.
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Methocel (HPMC) is a good choice as it stabilizes foam at the bubble/liquid interface thereby eliminating coalescence and promotes non-newtonian rheology is pseudoplasticity for easy spreading.PEG 150 if overused causes dilatant rheology (balling up or the reverse of pseudoplasticity ie does not spread well on skin/hair.
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You will also need safety testing on skin HRIPT with at least 50 panelists which runs about 1500USD:USP 51 microbial challenge-500$.Figure an additional 500 for moisturizer (TEML etc).Total is about 2500USD.
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you can use citric acid just do not go below 9.5-10PH—-If you want to superfat the soap use stearic acid to PH 8-8.5
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The HPMC is a solid that has to be heated first to disperse/wet it in water but goes into solution when you shock the dispersion in an ice bath while cooling down (see Dow bulletin on Methocel).Usually best to make a 3% stock solution and preserve it if held longer than a day:liquid is easier to work with.
PEG 150 DS will go in hot particularly with surfactants upon heating to 70C.
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correct typo above should be hydroxypropylmethylcellulose
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Hydroxypropylmethylcellusose HPMC yes in a shampoo base
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@zwapp You are right and thanks for your posts on Nisin -most interesting research as I am doing acne research also. Cheers
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The inulin is a prebiotic polysaccharide which is food for probiotics which in turn inhibit attachment of pathogens at least in the gut but doubtful it works on skin.Note there is no preservative in the formula! I would not trust the former mechanism in place of a functional preservative.
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Natural beeswax—-Koster Keunen, Inc.
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The net/net is if you use SIMUGEL in combination with Montanov 68 you should be okay with stability of emulsion.
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Septic does not use HLB because it is not neccasary.Note formulae have polymer SIMUGEL which negates need for HLB as most all polymers do i.e. Carbopols etc:however some still use HLB in combination.Personally we have found it unnessasy
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You see different levels because 1-each base is different in composition 2-each product is fragranced to suite the demographics of the audience to which it is marketed as fragrance can make or break a product.We submit base to 2-3 fragrance companies with a product concept together with a set price in $/cwt of finished product.The level is set by the Fragrance co, based on the price/cwt of finished product you are willing to pay.
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Do you have an analytical lab ? If not you need a contract analytical Lab who will instruct you:usually they want formula w/wo sunscreens and the actives you are using.Most labs here have the actives.Once method is validated you can run stability tests as per your regional guidelines (FDA).
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With a small panel i.e. 6-10 testing preference of each product blind versus Brand Used Most Often (BUMO) usually gives good feedback.If one stands out you will really see it but keep it simple and do not mix price in before you get the best product.Focus group is good for that with coffee and donuts.
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Could also be Hyrolyzed Oat Protein which is water soluble and provides a noticeable foam boost!
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I like the use of the Sarcosinate as it should provide a tight soap-lather.Tea tree Oil as preservative I am extremely skeptical it would pass USP 51:Sea salt may be okay but I have not used it.I would add a chelate such as Na2 EDTA for any heavy metals present from sea water.
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Glad to see people are still using time-tested parabens.I hesitated to recommend them but a good fit for your system.
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Based on formula you show should be ok as sulffosuccinate will provide creamy lather.You just need a preservative (1percent phenoxyethanol).Also watch viscosity in storage as the sulfocuccinate can be thixotropic (viscosity increase with time)
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The formula you post is a start.What is the final Ph? Plus before going into stability etc you will need a preservative.Since you intend this for use on sensitive skin suggest you use geoguard Ultra which will lower Ph to 5.
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I agree, as Scientists, we are not here to be demeaning to anyone:as People mutual respect should be an inherent attribute in providing information or direction.