PhilGeis
Forum Replies Created
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Can’t offer a risk assessment based on what your boss “thinks.” But I understand your position. Just make sure your “boss”, not you, is responsible on paper for this product.
https://www.usptechnologies.com/what-are-h2o2-stabilizers-and-will-they-affect-my-application/
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Yes - stop it. If you don’t know what’s in your ingredients, you should not be exposing consumers to your product.
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OK - it’s not as good and fairly useless vs Gram positives and fungi
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Doubt it’s anything special re. micro. More gee whiz - note they do not compare to other surfactants. Even marketing does not recommend preservative free.
Why phenethyl vs,. phenoxyethyl?
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Activated charcoal in cosmetics is useless.
You’ll need enough for consumers to see it when they use the product.
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Net contents must be right per MAV - not under or overfill.
Don’t want product squeezed lout merely holding the bottle.
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Amen Microformulation!! Recall an instance when poor process design had the preservative precipitate - filtration of “particles” left it unpreserved with predictably contaminated.
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Ethanol is your antiseptic active so 60% or greater. Very Very unlikely you’ll be successful with foaming.
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Curious re definition of sensitive. SLS innovation and success last century was for the resolution of problems with true-soap based products and hard water.
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Always use multiple preservatives.
1) no single preservative has true broad spectrum efficacy
2) it’s harder for a contaminant to adapt to multiple preservatives vs a single compound
Phenoxy is prob best 0.5%. ECT is over formulated
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Thanks. Pretty casual “science” published in a second rate journal. I’d not put too much significance to normal product use/benefit. They tested a product with 30% EMU oil, not the ingredients or vitamins; control/placebo was not defined; 11 subjects split between test and placebo in unidentified numbers; product application via pad was uncontrolled; technical benefits reported vs visual expression,; questionable interpretation (Fig 3 - claimed benefit when errors bars clearly overlapped).
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Sorry - 10% Emu oil.
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With some surfactants, the effective pKa of benzoate is increased making it effective at higher pH.
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the curse of Dabre - the partron saint of garbage science.
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Benzyl alcohol, Kathon and EDTA is a good combination.
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Unless you can are willing to chase a benefit in clinicals, cut it down to minimal levels.
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Imagine my surprise!! Ricky Mountain product development never got back with info requested.
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Hard to see how they “sterilize” and maintain as sterile packaging and raw materials and how thyey consider Aw in context of an emulsion.
Asked for validation through consumer use - they forward to their product development.
Let’s see.
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here’s what they said, it’s BS
Products can be made with zero preservatives (oat lotion) adhering to the following conditions:
Use 100% sterile raw materials
Use 100% sterile packaging materials
Follow strict GMP from start to end, as listed below.
Design the product as very low water-activity
Maintain the pH in the 4-6 range
Use raw materials which act as pseudo-preservatives.
Minimize human (user contamination).
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Not aware such data exists for others.
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correction …… with the right challenge test.
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One can see the impact in challenge test results - with the right challenge test resukts.
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What do you think is caffeine’s impact on those conditions?
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0.7 prevents growth, does not kill. For emulsions Aw may not matter.
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I have some insight re. this - the active is not the only “tricky” element.