Home Cosmetic Science Talk Formulating Disinfectant

  • Disinfectant

    Posted by ChE28 on October 8, 2023 at 10:26 pm

    Hi. Can you help me? I am formulating a disinfectant with guava extract , centella asiatica extract and aloe vera extract. I noticed that when I add more ethanol, the solution became clear. My worry is how much ethanol is too much for wound disinfectant since we all know that when alcohol is added to wounds, it stings. Thank you so much.

    ketchito replied 9 months ago 5 Members · 11 Replies
  • 11 Replies
  • PhilGeis

    Member
    October 9, 2023 at 7:53 am

    Is this for personal use or to be marketed - and in what country?

  • ChE28

    Member
    October 9, 2023 at 5:47 pm

    We will market it here in the Philippines.

  • PhilGeis

    Member
    October 10, 2023 at 6:04 am

    You should check Philippine regs.

    60-95% is the typical range - but please be aware the aloe and guava may screw up your efficacy.

  • Zoya

    Member
    October 10, 2023 at 7:35 am

    Hello.

    As Phil mentioned, check your country’s regulation and take your other ingredients under consideration, as they may reduce the efficacy of your product . Otherwise, this may be useful: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132458/

    but there are plenty more articles on this topic.

    Higher concentrations usually sting when applied to a wound, but you probably need higher content of ethanol for proper efficacy, if this is the only desinfectant in your formula.

  • ElmiraHara

    Member
    October 16, 2023 at 2:27 am

    Any update?

    • ChE28

      Member
      October 17, 2023 at 7:13 pm

      Hmm. I guess I didn’t explain well my questions. Because the active raw material in this formulation is guava extract, centella extract and aloe vera extract. Ethanol is just a solvent. So I am also wondering if this product will be used as wound disinfectant. For a short background, this product already has formulation and I was just trying to improve its appearance however the previous formulator only had 1% ethanol and my formulation now has 5% ethanol. So I didn’t know if that was too much.

      • PhilGeis

        Member
        October 18, 2023 at 5:58 am

        As a “disinfectant” - antiseptic, ethanol is an active. How/to what action/efficacy are guava extract, centella extract and aloe vera extract “actives”?

  • PhilGeis

    Member
    October 19, 2023 at 4:44 am

    Disinfectant?

  • ketchito

    Member
    October 19, 2023 at 7:16 pm

    I agree with @PhilGeis . Choose carefuly your sources and read with critic eyes. That journal has a very low impact factor (ca. 0.1). This is not a perfect metric, but it will help you filter papers.

Log in to reply.