Microformulation
Forum Replies Created
-
No. I would never recommend it as a client-use product UNDER ANY CIRCUMSTANCES whatsoever. For safety and liability, it is negligent to do otherwise. As such it wouldn’t be a Primary Acne Treatment. I have made hundreds of these in both Pharmaceutical Compounding as well as a Consultant. It is not a limitation to take lightly.
The attached reference discusses the treatmet and indications for Jessner Solutions. They are a Derm Care Product.
Also, you will not achieve a stable product without particulate matter with 70% Ethanol. It uses 95% Alcohol. Try as you might, the solubility doesn’t favor your substitution.
-
The Jessner and Modified Jessner products are made with 95% Ethanol. That is a factor as well.
“Jessner’s Solution has been used for over 100 years as a therapeutic agent to treat hyperkeratotic epidermal lesions. This superficial peeling agent constitutes a mixture of salicylic acid, resorcinol, and lactic acid in 95% ethanol.” (Dr. James Dolezal, Delasco)
-
Your Formulator doesn’t have to be FDA Registered. They should however have experience with OTC products, the monographs, OTC documentation standards, and other specific tasks. Sunscreens are deceptively easy. There is far more to it than simply adding SPF to a product.
-
What has your research shown so far?
-
A few weeks ago, we experimented with the AI model, and we found that it
still has a considerable amount of progress to make. We encountered
similar problems when seeking formulation advice. What was even more
concerning (and we thoroughly tested this multiple times) is that when
we encountered regulatory issues, the model often referred to
do-it-yourself (DIY) sources from the first page of Google search
results, without citing any technical references or official
regulations. -
Assessing the stability of a formulation solely based on written
documentation is inadequate. To obtain accurate and reliable results, it
is essential to produce a physical sample and conduct comprehensive
stability studies. -
The majority of certifications available in the cosmetics industry have
limited utility for start-ups and growing lines. With the exception of
the USDA NOP Organic certification, which holds value in specific
markets, the benefits of these certifications are unclear. Notably,
certifications like NSF or Ecocert are unfamiliar to mainstream clients,
thus providing no competitive advantage.When clients embark on creating “natural” cosmetics, they often lack a
clear direction. Consequently, the product design phase becomes
challenging, resembling herding cats. Clients may resort to unreliable
online sources to scrutinize unfamiliar raw materials. Introducing a
certification standard, even with its potential imperfections, can
streamline the product design phase. -
I would have to weigh in and agree with @PhilGeis
I work with some emerging lines/start-ups and there is a great deal of naivete with many DIYer’s. In one case a “highly successful” DIYer presented us with their net/gross revenues. It was less than the amount we paid for cleaning supplies at a Contract Manufacturer.
In our experience, it isn’t even a Technical issue but a Business issue. Some may see this as heresy, but Cosmetic companies survive with Good Business practices and Effective Marketing. If you want to avoid plateauing early on, you must have a Business Plan and the liquidity to move forward.
-
A salon product is applied by a skincare practitioner in a treatment setting.
Again, even if your Region has no Regulations in this regard, it is still a safety issue with potential liability issues.
-
Honestly, you are looking for a simplistic answer for an issue that you really need to study more broadly. Again, preservation is hardly a simple matter of adding the right preservative, mixing, and forgetting. There are multiple issues you need to consider. A Preservative System is very much Formulation Dependent. There are other additions you should consider such as chelants, glycols, etc.
I would suggest doing some reading on Preservation from a reputable learning source. As most Professional Chemists can attest, we have to remain diligent and continue to learn about new options as well.
-
While economics certainly come into play, sadly there is not one size fits all preservative. Your preservative system is Formulation dependent in many aspects. Restricting it based on procurement/price issues may cause you to compromise regarding safety in many cases.
-
I have used this product (as it was required by the marketers in the Product Design). Honestly, we didn’t see a great deal more moisturization as perceived by the user. Ironically when they started pricing out the projects, they had us sub it out with plain Glycerin.
-
While your Region may be different, in the US that product would be “For Professional Use Only” and restricted to application in a Treatment setting. You may want to reconsider your pH.
https://www.fda.gov/cosmetics/cosmetic-ingredients/alpha-hydroxy-acids
-
I see worse all the time. DIYer’s trying to get established in a retail market are, in my experience very uniformed on Regulatory issues.
https://www.fda.gov/safety/report-problem-fda/consumer-complaint-coordinators
fda.gov
Consumer Complaint Coordinators
Report an adverse event or problem with an FDA-regulated product to a Consumer Complaint Coordinator.
-
Welcome to Microformulation Cosmetic Consulting LLC! We are here to assist you with all your Cosmetic Formulation Development needs. Our dedicated team specializes in Product Development, Formulation Design, and Testing, working closely with clients like you to bring your ideas to life.
Finding the right resources for your project can be challenging, but worry not! We’re here to help you find and retain the best contract manufacturers, private label sources, marketing consultants, and regulatory experts. Our goal is to ensure that you have all the support you need throughout the entire process.
With our Technical Director boasting over 30 years of experience in the pharmaceutical, over-the-counter (OTC), and personal care markets, you can trust that you’re in capable hands. We understand the ins and outs of the industry and can guide you through any obstacles you may encounter, ultimately helping you bring your product lines to market successfully.
If you’re aiming to meet major natural standards such as COSMOS, NSF, NPA, Whole Foods Premium, and others, we’ve got you covered. We specialize in formulating products that meet these standards while prioritizing safety, effectiveness, and affordability. Together, we can create cosmetic products that align with your vision and meet the highest quality standards.
In addition, we have been working closely with the CBD (hemp) and cannabis-based CBD industries since 2015, providing valuable expertise in manufacturing, formulation, and regulatory matters specific to these industries. We understand the unique challenges and requirements involved, and we are ready to assist you every step of the way.
When it comes to cosmetic product development, we offer a comprehensive range of services to cater to your specific needs. From refining your product definition to designing the perfect formulation, creating prototypes, conducting stability testing, and transferring ownership of the formula to you, we’ve got you covered. We can also help you connect with other service providers such as manufacturers, packaging providers, and testing labs.
At Microformulation Cosmetic Consulting LLC, we are dedicated to making your cosmetic product development journey as smooth and successful as possible. Let us be your trusted partner in bringing your ideas to life and creating exceptional cosmetic products that leave a lasting impression.
-
I have utilized sucrose in hair fixatives. Other than the issues cited above, I would encourage you to look at the reviews for similar products. Clients experience horrible product sensorials when these products are rewetted due to precipitation or grooming. In the end, you can create a superior product with better, more stable, yet “naturally compliant” raw materials.
-
It won’t work with 70% ETOH. I can tell you that from personal experience.
-
It is advisable to direct those questions to someone with expertise in a Clinical setting. Our involvement was limited to the compounding
aspect, and we were not directly involved in the treatment process. -
And…what ingredients absorb in the skin? I’m always a bit skeptical of that claim. My first undergrad Internship was doing QA on Transderm Nitro patches. I spent an entire summer in a windowless room doing calculus-based Pharmacokinetics. Transdermal absorption is rarely achieved. Were a product actually absorbed it would arguably be a drug.
-
I primarily direct my educational efforts toward my two technicians. Rather than providing them with all the answers, I believe in fostering their knowledge through on-the-job learning. Although they may occasionally find it challenging, I have a specific approach when they come to me with a problem that can be easily researched: “What have you found through your research so far?” Whenever one of them is able to teach me something new, I secretly derive a sense of satisfaction.
Regrettably, achieving a similar dynamic in DIY groups is often challenging due to the reluctance of many individuals to accept mistakes or guidance.
-
I’m not trying to be pretentious or difficult, but I can’t discuss that particular INCI Deck in-depth due to a contractual issue. All I can say is that the Original Formulator, Dr. Dolezal used that as a pH modifier and for functionality.
-
I can understand where you’re coming from. While working as a consultant, I haven’t had to interact with marketing teams as frequently, and we typically have more influence and involvement in decision-making. However, during my time collaborating with a contract manufacturer, I found that the marketers in the front office often posed more of a hindrance than assistance. Instead of supporting the technical department, they seemed focused on showcasing their own abilities. During status conferences, they would arrive armed with extensive notes from industry watchdogs, such as the EWG, intending to “challenge” the technical team.
Of course, there were some exceptional marketers I encountered along the way. I remember one individual who displayed genuine interest in our work and respectfully requested to shadow us in the lab while asking insightful questions. It was clear that she possessed a deep understanding of the field. In due course, she advanced her career and became a product manager at a well-known mid-sized cosmetic company.
-
-
In Compounding Pharmacy, “Remington’s Science and Practice of Pharmacy” served as a reference guide. According to this authoritative source, a pH of 1.9 was considered the standard for certain solutions. However, it is important to note that pH adjustments may be necessary to achieve the desired pH level as specified by the formulation.
-
The Jessner and “Modified” Jessner Solutions, once prepared, were typically sent directly to the clinic or issued to the Dermatology Clinic through prescription. It is crucial to emphasize that these solutions were never directly provided to a patient, client, or customer. This approach is due to the inherent liability associated with the product and the importance of proper administration under proper supervision.
Honestly, if you are going to make an aggressive peel and you don’t care about the “Professional Use Only” precautions, you should look at Jessner and Modified Jesner Solutions.