Microformulation
Forum Replies Created
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Generally people use Excel.
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mikethair said:I have developed a system using Excel. Works for me, and have been using the approach for 15+ yearsAnd also, keep inventory to a minimum unless you are a manufacturer. The Regulatory requirements for Raw materials, if you are going to be compliant, cover far more than just maintaining an inventory list.
And that is just the tip of the iceberg. -
No, you would have to declare the INCI names, not an internally assigned marketing name.Many companies already offer these Petrolatum alternatives. We have used some great ones from Sonneborn.
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The main difference between dog and human products is that
ingredients in pet formulations in the U.S. require approval in line
with the Toxic Substances Control Act (TSCA). Also, dogs’ skin pH is
slightly higher, 7.0, and slightly less acidic than that of humans,
which is in the 6.0 range, according to Guiliano.
“Formulations or ingredients that you use on people or in products
meant for humans can also be used on your pets, you just have to confirm
with the regulatory requirements,” she said.https://www.basf.com/us/en/media/featured-articles/Products/pet-grooming.html
BASF has some great info for this sector.
My best advice, without getting too detailed, is to track your raw material costs closely. If you look at the market leaders you will see that sulfates are common in this sector. Be very careful and shrewd business wise before deciding that you can make a “Prestige Pet Care” product and position at a higher price point. Learn the market. I am aware of the spending trends in this market (we support our local Animal Shelter in various ways), but I have had so many clients learn this the hard way.
Essential Oils are advocated by some “natural” lines, but I would investigate the safety of any EO you utilize. There are some possibility’s for adverse reactions.
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Here is the HAPPI Manufacturers Directory, a good starting point; https://www.happi.com/directory/C_US/buyersguide/services
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There are only a dozen facilities in the US that practice cGMP? I have to disagree.
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abierose said:Microformulation said:We maintain very few samples in inventory. We are able to get samples of just about anything via UPS in 5 days or so. Also, our goal is to do R&D, not store keeping. Except for the most common staples, we maintain little inventory and it has never slowed down a project. The project samples are maintained in a climate and humidity controlled space.
And when you say “climate and humidity controlled space” are you talking about a small room, locker, cabinet, large humidor….? ???? sorry if this is a silly question..it’s just I’m in such early stages of all this and I have quite a large number of samples and ingredients that I would like to store in the best way possible to avoid spoilage as well as to be more organized…
If you are maintaining an inventory, are you maintaining MSDS’s and TDS’s for the materials? (You may not believe this is a requirement, but my local Code Enforcement has the requirement AND it is the proper way). Also, are you reinspecting samples at their projected “use by date?” These (and many other issues) are why maintaining a sample stock can be time consuming. Also, even if you are small, you should be still completing these requirements.
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My entire lab is cooled/heated with it’s own zone and we track humidity. It is 1200 sq ft so we have plenty of space. Again though, as @MarkBroussard mentioned, you should keep samples in a project bin. If you are a credentialed lab it is easier to get samples for each project than to enact a store keeping/inventory program in my experience.
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We maintain very few samples in inventory. We are able to get samples of just about anything via UPS in 5 days or so. Also, our goal is to do R&D, not store keeping. Except for the most common staples, we maintain little inventory and it has never slowed down a project. The project samples are maintained in a climate and humidity controlled space.
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I will tag in @Belassi
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You may want to reconsider Kathon CG (methylchloroisothiazolinone, methylisothiazolinone) in a Pet Shampoo. There are some pending class action suits. It also is beginning to get pushback from the pet market. I would research these issues.
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Like Perry, I am puzzled why this info is important, but likely you would have to do a patent search as a first step.
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It is likely you will need to look at products that aren’t “less toxic and mostly with natural components”, terms that really aren’t very useful in R&D.
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You would need to share the Formula for anyone to really objectively weigh-in. Also, what are you using for mixing equipment?
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Many starting Formulas are just that, a jumping off point for a Formulator. Keep in mind that they a. highlight the distributors raw materials over others and b. they are so broad that they really can’t address a clients specific marketing and claims.If you look, usually they have the mission of highlighting an emulsion system, a preservative system or some other specific material they are selling.
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The anecdotal evidence in this post is persistent. There are ways to quantify these results. What instrumentation has been used? Has a Claims Substantiation Service (crucial) weighed in?
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I fall into a different school of thought. We transfer ownership of the Formula (IP) to the client as part of our fee. Honestly royalties rarely are profitable, our Formulas are designed to meet their Marketing benchmarks, any Formula can be knocked off, and lastly the product will succeed solely on their marketing.
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How long was it in stability? Generally in my experience it can take up to the second or even third 28-day testing periods to see oxidative changes.
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Honestly, we have never found a software package that met all our needs, so we created one with Excel templates and Microsoft Access. Fortunately it also was easy to utilize with a tablet. We are tablet-based in the lab now.
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You will need to do your research, but that is a “formula” that made it’s way around some of the DIY blogs a few years ago. It is pretty widely copied.
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It depends on multiple issues such as final desired viscosity BUT the answer is only going to be derived at the lab bench, empirically.
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Don’t use an immersion blender, that simple. They are not used in R&D for this and numerous other reasons. With an overhead mixer and the proper blade, you can limit cavitation to such a level the the incorporated airissue is moot.
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If you post the Formulation with percentages, you will get better answers. I would guess it is likely an issue with the Niacinamide and you should research this issue closer. However, without percentages this is simply a guess.
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I hardly doubt you would create Carbopol at the local level. You would be best served by simply purchasing this product.
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The Forum isn’t really meant to be a place to ask for Formulations outright. If you need a Chemist; https://chemistscorner.com/cosmeticsciencetalk/#/discussion/137/need-formulating-services-here-are-some-contacts