David
Forum Replies Created
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@Bobzchemist - is addition of the combination pemulen/carbomer really leading to a more constant viscosity in the above mentioned temperature interval? If so. that is valuable information!
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“To activate the nanoparticles shake the bottle before each use” !! good one, haven’t seen that before :smiley:
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nice webdesign… is it selling? @Wiktoria25
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The graph is alright except it doesn’t show the interval of interest associated with the problem. We need to know what xA is when X1 is higher than 0,4
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For the steroids a GC-MS would come handy.
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Looking for unknown compounds in an unknown matrix is a very expensive and complicated story. If you just give a sample to a lab you won’t get an answer unless you give them a clue what they have to look for. A task like that can in theory keep a research team busy for decades (even in a top modern analytical lab).
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Nice - thanks.
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I always felt it is a bit of “cheating” to use a polymer to stabilize an otherwise unstable formula. On the other hand that is of course just nonsense - so go for it! There are many options . .(pemulen, aristoflex, carbopol etc) .
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@PharmaSpain good point.
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with that amount of EtOH you may not need a solubilizer, did you try to dissolve the perfume in alcohol? For the color : add EDTA or as @Belassi says change color. I’ve had some success with tinoguard - but yeah they are quite expensive
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That’s indeed really funny, didn’t realize hair starts to burn at that temperature. 🙂 Croda however promises “outstanding heat protection” up 220C with their Mirustyle, Sounds still pretty high to me…
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I should have added that it is not a product specially made for blow drying
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the standard fragrance solubilizers in cosmetics are peg-40 hydrogenated castor oil or polysorbate 20
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Ok we are chemists but who wants to sell a cream that has failed QC, then irradiated or post-preserved? At least I wouldn’t.
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It is indeed frustrating when stability tests don’t show the same change, one reason a stability test can’t be standardized. Check first what the difference may be. contamination/packaging as @Bill_Toge says (try to use same packaging for stability tests)- or any other factor that may differ. light situation- oxidation (of peppermint oil?) - production method . pH etc,.
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@MarkBroussard @BartJ In EU there is indeed sometimes a different regulation for professional use like here . In the case of salicylic acid, however, the same rules apply for professionals as for general users.
As I stated above : Max 3.0% rinse-off Max 2.0% in other products. -
Thanks @Microformulation I would definitely give it a try if the client was in the EU - but I feel the distance is to far and also regulations may differ.
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indeed forget the silicone - your formula lacks a refattener like the good ol’ cocamide DEA -or an emmolient like @ashish stated
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Salicylic acid in EU: Max 3.0% rinse-off Max 2.0% in other products
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-or notepad
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have seen a few of formulations - they don’t seem to be to complicated - carbamide peroxide - carbomer - sweetener - stabilizer..
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one more
Transgel 110 : Paraffinum liquidum/ Caprylic/Capric
Triglyceride and Hydrogenated Styrene /
Isoprene Copolymer by Aiglon -
I am not an expert in this area either but are you referring to “real” dentist teeth whitening with high% of carbamide peroxide or just normal cosmetic toothpaste?
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I don’t think anyone has done that yet due to that there are so many different reactions and raw materials involved in cosmetics. For surfactants you can find a lot. e.g. here For new materials (like new silicone derivatives) I suppose the reaction path is partly confidential. Anyway it wouldn’t hurt to know more about the synthesis basics as a cosmetic chemist.
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@PharmaSpain It is actually an interesting point that you never can vary only one ingredient in a formula - you have to vary at least 2 or more