• Advanced Questions

  Hydrolysis

  Posted by belassi on April 28, 2018 at 10:23 pm

  Does anyone know if it is possible to hydrolyse protein with TEA? (As compared with NaOH or KOH)

  belassi replied 6 years ago 3 Members · 4 Replies
• 4 Replies

• 

  Bill_Toge

  Member

  April 30, 2018 at 8:53 pm

  I should think it’s possible, but it’ll be a hell of a lot slower as TEA is a significantly weaker base

• 

  DRBOB@VERDIENT.BIZ

  Member

  May 1, 2018 at 2:50 pm

  probably very slow with low conversion of protein to amino acids.You may have to recycle the underacted protein to make process cost effective.Increase catalytic alkaline protease may help but questionable.

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  Bill_Toge

  Member

  May 1, 2018 at 9:26 pm

  actually, now I think about it, I realise TEA is also a lot less nucleophilic than hydroxides, so you’ll be lucky to get any hydrolysis at all

• 

  belassi

  Member

  May 1, 2018 at 9:33 pm

  OK, thanks, guys.

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