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HELP: Panthenol (B5) turning pink
I have made a b5 serum a few times now and it is turning pink after 24 hours. Why?
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5 Replies
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Without a list of all the ingredients in your formula, it is difficult to give you any answer.
My blind guess is that your product is contaminated with bacteria.
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Simple formula:
- HMW HA 1% with DI water
- pantheon: I’ve tried both liquid and powder (d- and dl-) and it happens every time
- euxyl K712
No contamination, did mico tests on each batch Seems more like an oxidation? But this sent something that is document anywhere that I can find.
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Well, there are no obvious answers. However, I’d suggest you do a simple knock-out experiment to isolate which ingredient might be causing the problem. A knock-out experiment would simply be a series of batches each of which is missing one ingredient. You would replace the missing volume with water. So, if your batch normally calls for 1% HA, you would add 1% extra water instead. Then see which batch turns pink.
It could be lots of things. Metal ions in your water, oxidation of ingredients, some unknown contamination in your ingredients, etc.
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Do you have a fragrance? Some fragrance components can can turn pink under certain conditions.
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Whenever I hear of a drastic color change in something like this I look for the possible chromophore that would create that. In this case the aromatic benzoic acid comes to mind, otherwise…almost hate to suggest it…a nitrosamine (dangerous but colorful!) formed in combination with the amino functional group on panthenol? Hope not, but DEL the benzoate and see what happens.
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