Can silicones really provide occlusiveness to reduce Trans Epidermal Water Loss TEWL?
It looks like silicones don’t:
Results: Both petrolatum and silicones significantly decreased TEWL 15 min after application, but the measurements for the silicones were not significantly different from the untreated control values. The tested silicones did not moisturize the skin. Petrolatum formed an occlusive layer, creating an increase in skin hydration for more than 4 h. The results measured for the W/(O + Si) creams indicated that they moisturized the skin, without any effect on TEWL.
Conclusion: A clear difference was shown between the skin occlusive properties of petrolatum and the water vapor permeability of the common silicone excipient materials.
Occlusivity…Most silicone fluids are recognized as non-occlusive. Some organically modified silicone products such as stearoxytrimethylsilane and stearyl alcohol do provide considerably greater occlusivity than mineral oil although significantly less than petrolatum.
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