Members Directory - Chemists Corner

PhilGeis

Member

October 16, 2021 at 10:48 am in reply to: Microbiological growth in rinse off products.

Suggest CMIT/ Na benzoate /EDTA unless you formulate to be politically-correct. Good luck with that.

PhilGeis

Member

October 16, 2021 at 10:15 am in reply to: How do they support this claim and what ingredient does it? (Up to 95% less hairfall)

Abdullah said:

@PhilGeis good point but how you claim and support it is very important especially in a product that doesn’t do what people think it does for example reducing hair fall by shampooing it.

Not sure I understand - if you haven’t support, haven’t applied some metric in development that demonstrates, the claim is fantasy - pretty common in cosmetic biz.
If you’re asking how to communicate a product benefit valid or fantasy - that’s marketing/advertising.

PhilGeis

Member

October 16, 2021 at 10:02 am in reply to: Microbiological growth in rinse off products.

MurtazaHakim said:

Is proxel 106 a suitable preservative to be used for hand soaps ???

No. It’s formaldehyde with CMIT/MIT. The formaldehyde is not needed - as it shares efficacy with CMIT. It’s intended for paints coatings etc. where manufacturing contamination is typically pretty bad and the two strong preservatives help against resistance development.. Think some folks consider formaldehyde presence in head space in can discourages mold.

PhilGeis

Member

October 15, 2021 at 10:57 am in reply to: How do they support this claim and what ingredient does it? (Up to 95% less hairfall)

Consider testing your product to any claim - rather than looking for support.

PhilGeis

Member

October 15, 2021 at 10:54 am in reply to: What does skin protectant do?

https://www.federalregister.gov/documents/2003/06/04/03-13751/skin-protectant-drug-products-for-over-the-counter-human-use-final-monograph

PhilGeis

Member

October 14, 2021 at 2:08 am in reply to: Microbiological growth in rinse off products.

ariepfadli said:

Try with formaldehyde releaser such DMDM Hydantoin, imidazolidinyl urea, etc. They effective and safe for rinse off products

Good ones above but recommend as best Na benzoate/chloromethyl isothiazolinone /EDTA.
However these are manufacturing contaminants - appears you need major improvement in manufacturing hygiene and GMP’s. Preservatives are largely intended to protect during consumer use.

PhilGeis

Member

October 13, 2021 at 10:54 am in reply to: Soap Bar Manufacture

Are you in US ?

PhilGeis

Member

October 12, 2021 at 4:40 pm in reply to: What is the appropriate preservative ?

Abdullah pointed out you have a system. Be aware, for wipes you must challenge test the wet wipes - not just the fluid.

PhilGeis

Member

October 12, 2021 at 10:11 am in reply to: Best way to sterilize plastic bottles

No one sterilizes and you don’t need sterility. You probably don’t need to use any - are the bottles clean?

PhilGeis

Member

October 11, 2021 at 10:28 am in reply to: Does 20% sodium chloride in water need preservative?

Not sure there is a limit or at that level concern is more potential than reality.
Yup 35% by weight.

PhilGeis

Member

October 11, 2021 at 10:21 am in reply to: Preservative does my formula needs?

Sodium phytate is a good chelator. Stay with it.

PhilGeis

Member

October 11, 2021 at 10:20 am in reply to: Is store-brand distilled water reliable?

Graillotion said:

I never read the label on my distilled water before tonight. Is says:
Processed by: Steam distillation, microfiltration, ozonation.

So is that the trifecta….as good as I could hope for from a big box store purchase, @PhilGeis ?

Ozonation helps., it’s typically used for bottled water. Go with the test

PhilGeis

Member

October 10, 2021 at 11:54 pm in reply to: Does 20% sodium chloride in water need preservative?

Pharma - and worse - the damned things are so hard to culture, it takes forever to figure out the problem (discolor, clouding, slime) is microbial.

PhilGeis

Member

October 10, 2021 at 6:34 pm in reply to: Does 20% sodium chloride in water need preservative?

Moderate halophiles can grow up to 20% salt and halophiles are among the contaminants of many household and industrial products - minerals/salts themselves are often the source.
Pharma makes a good point - they are heat sensitive. Boil it and seal it - or take your chances.

PhilGeis

Member

October 10, 2021 at 5:03 pm in reply to: Does 20% sodium chloride in water need preservative?

20% is not prohibitive to microbial growth.

PhilGeis

Member

October 10, 2021 at 4:57 pm in reply to: Preservative does my formula needs?

That means very little - it’s a poor preservative

PhilGeis

Member

October 10, 2021 at 3:59 pm in reply to: Preservative does my formula needs?

Leucidal is not a very effective preservative.

PhilGeis

Member

October 10, 2021 at 11:15 am in reply to: Is store-brand distilled water reliable?

Just use the paddle media every time you formulate. These are very poor for products but not so poor with water.
Decide upfront what result will cause you to toss the product you made.

PhilGeis

Member

October 9, 2021 at 12:47 pm in reply to: Is store-brand distilled water reliable?

Mine is industrial experience - recirculating water systems with ozone and heat. Maybe contact the manufacturer - they might be ozonating.

Preservatives are intended to protect consumers in use - not correct for poor GMP’s. Even a “good” preservative system can be overwhelmed. Our systems are weak - not accomplishing in a month what a disinfectant does in 10 minutes or less. They have to be weak or they’d not be safe in use.

PhilGeis

Member

October 9, 2021 at 9:46 am in reply to: Is store-brand distilled water reliable?

Microbial content of water is dynamic. Cepacia, ~ the most common cause of recall, can grow to millions in a day in distilled water. Water is the most problematic ingredients - you don’t know micro quality at formulation until days after the product is made and packaged.