PhilGeis
Forum Replies Created
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Glycols have been used but can irritate
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Even with a relevant pH, think benzoate alone is a risky preservative system.
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PhilGeis
MemberJune 6, 2024 at 6:02 am in reply to: Need help formulating a clear gel face cleanserVery very poor preservation. Does your policy allow phenoxyethanol? Benzoate if pH works?
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PhilGeis
MemberJune 5, 2024 at 6:13 pm in reply to: Specifications and acceptable range for OTC sunscreen actives -
PhilGeis
MemberJune 5, 2024 at 8:05 am in reply to: Stability of CMI MI & formalin at pH 10 for ~30 minutesDoubt it’s stable. CMIT in any simple aqueous solution is unstable and alkaline pH is tough on it as well.
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PhilGeis
MemberJune 5, 2024 at 4:49 am in reply to: Not good enough preservation system? Or bad production?Benzoic acid? or Na benzoate? should be 5000 ppm should be enough.
Would you consider this a water or oil in water
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PhilGeis
MemberJune 3, 2024 at 4:20 am in reply to: For each case one specific product need stability test for quality control?If your anticipated development is rapid and includes multiple minor changes/versions, you can determine, if technically justified, which modification justify full stability qualification or stability before marketing.
To Mike’s point, it is important to comply to relevant regulations but do not consider government regulations technically useful or valid. Do what is necessary to comply AND look to industry standards to do what is technically valid.
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PhilGeis
MemberJune 2, 2024 at 12:15 pm in reply to: What is, the best alternative for Aluminium chlorhydrate for dedorant?Aluminum chlorhydrate and related monograph monograph actives are antiperspirants - not deodorants. Not aware any of options named above would be functional and certain none would be legally used to support antiperspirant claim in US.
For product claiming “deodorant” - you can use anything (or nothing) but in US not Aluminum chlorhydrate and related monograph actives.
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Suggest you do not. If you receive it clean - appropriate sanitary practices of sampling and use should not pose a risk.
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Doubt you’ll have obvious mold growing on your consumers’ faces. Perhaps mold/bacterial contamination of your product.
Food quality ingredients often fail to meet cosmetic microbiological standards.
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PhilGeis
MemberJune 11, 2024 at 10:19 am in reply to: Pentylene Glycol and Preservative 12 CompatabilityGluconic acid isn’t that great. If you hold Phenoxy/EHG to 0.80% or less would you consider 0.1% EDTA? You’d still be 99% natural.
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PhilGeis
MemberJune 11, 2024 at 9:29 am in reply to: Pentylene Glycol and Preservative 12 CompatabilityThanks Olivia. Your understanding is not uncommon but is profoundly inadequate. I don’t see a preservative in the formula you describe just above. Please add a chelator AND a preservative
Please understand “cosmetic assessors” are junior bureaucrats with little knowledge of cosmetic microbiology. The concept is a product of even more ignorant regulators, the folks who brought us the total BS of PAO. Assume they’ve given thumbs up based on some version of challenge - ISO, USP, EP - tests that are not validated in any context. They do show baseline efficacy that, with clean RM’s and sanitary manufacturing, can get clean product out the door. However, The primary purpose of cosmetic preservation is protection in use.
A 6 month sell by date is absolutely meaningless. Even if compliance (how is that enforced?), the consumer will have the product for more months, even years through which preservative stability must be maintained. Major manufacturers who validated their preservatives to in use risk establish stability for 3 years.
Please add a chelator AND a preservative
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PhilGeis
MemberJune 9, 2024 at 1:29 pm in reply to: Pentylene Glycol and Preservative 12 CompatabilityYes - a preservative is essential and a chelator is part of it. try phytic acid
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PhilGeis
MemberJune 7, 2024 at 8:32 am in reply to: Need help formulating a clear gel face cleanserSure - but more than you need and some junk “preservatives”.
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PhilGeis
MemberJune 7, 2024 at 5:00 am in reply to: Need help formulating a clear gel face cleanserSuggest not. Gluconolactone is a something if a chelator that breaks down to gluconic acid,
pH works for Benzoate and true synergism has been reported for it with Benzyl alcohol and a chelator. Do you have challenge testing capabilities?
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PhilGeis
MemberJune 6, 2024 at 2:04 pm in reply to: Need help formulating a clear gel face cleanserPackaging helps - assume cold process.
Sure - a chelator is always good. What’s pH?
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PhilGeis
MemberJune 6, 2024 at 11:23 am in reply to: Need help formulating a clear gel face cleanserThe combination is also quite weak as is benzoate alone.
What is your packaging?
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PhilGeis
MemberJune 6, 2024 at 5:56 am in reply to: Stability of CMI MI & formalin at pH 10 for ~30 minutesI don’t have much good information to share on that. I do understand formaldehyde is more reactive at alkaline pH. In another context I’ve used formaldehyde @pH as preservative 10 for an industrial product - uniquely effective combined with EDTA. Long term stability was not evaluated.
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PhilGeis
MemberJune 5, 2024 at 10:56 am in reply to: Not good enough preservation system? Or bad production?might be a bit weak v. Gram -‘s
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PhilGeis
MemberJune 5, 2024 at 6:02 am in reply to: Not good enough preservation system? Or bad production?500 is not enough. Suggest 2000-3000 ppm
Sorbic is not so stable and I’ve not seen the “synergy” many claim.
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PhilGeis
MemberJune 5, 2024 at 5:39 am in reply to: Not good enough preservation system? Or bad production?500 or 5000 ppm? 0.05% is 500 ppm.
Think Na benzoate would be preferable.
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PhilGeis
MemberJune 5, 2024 at 4:53 am in reply to: Antiperspirant roll-on deodorant turn yellowishNo pH 3-4 is not low enough.
What is the entire formula?.
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PhilGeis
MemberJune 3, 2024 at 4:10 am in reply to: What is, the best alternative for Aluminium chlorhydrate for dedorant?For a deodorant. The claim is not regulated - they can use what they want without the burden of efficacy.
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Probably not.
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Suggest you look also at similar products from major guys on the market