Members Directory - Chemists Corner

PhilGeis

Member

March 14, 2022 at 4:04 pm in reply to: Euxyl PE 9010 and it’s “smell”

yes

PhilGeis

Member

March 14, 2022 at 1:09 pm in reply to: Euxyl PE 9010 and it’s “smell”

Suggest phenoxy max 5000 ppm. If that isn’t effective, greater level is unlikely to help.
Sorbate as unsaturated molecule can undergo oxidation.

PhilGeis

Member

March 14, 2022 at 1:04 pm in reply to: Dishwashing liquid is too acidic

You’ll not form a soap per se - but dishwashing detergents are typically alkaline. Suggest adjustment to ~ 8-9 with NaOH. You might also consider a preservative. Look at Dawn https://dawn-dish.com/en-us/how-to/what-dawn-is-made-of-ingredients
Why mag sulfate? for viscosity adjustment?

PhilGeis

Member

March 13, 2022 at 3:25 pm in reply to: Euxyl PE 9010 and it’s “smell”

Could “smell” may also be due to sorbic acid instability/oxidation?

PhilGeis

Member

March 10, 2022 at 3:14 pm in reply to: Product contamination by which of these microorganisms can increase the pH of product?

Doubt much info - but product ingredients prob would be functional - sugars, amino acids, protein,

PhilGeis

Member

March 10, 2022 at 2:31 pm in reply to: Product contamination by which of these microorganisms can increase the pH of product?

what product?

PhilGeis

Member

March 10, 2022 at 9:33 am in reply to: What are the resources you would need to begin getting US FDA approval for sunscreen?

FDA does not “approve” specific sunscreens. They are made in compliance to the relevant monograph, drug GMPs, etc.
https://www.accessdata.fda.gov/drugsatfda_docs/omuf/OTCMonograph_M020-SunscreenDrugProductsforOTCHumanUse09242021.pdf

PhilGeis

Member

March 10, 2022 at 9:26 am in reply to: Preservative for mineral sunscreen

Prob best to examine mineral sunscreen labels of major manufacturers.

PhilGeis

Member

March 8, 2022 at 11:11 am in reply to: Propylene glycol irritation. I thought this was a rather benign ingredient?

Glycols at higher conc’s can irritate. It is often transient, disappearing with continued product use as iwith relevant deodorants,

PhilGeis

Member

March 7, 2022 at 6:20 pm in reply to: Preserving a Foaming Sugar Scrub

What is surfactant?

PhilGeis

Member

March 7, 2022 at 10:37 am in reply to: Preserving a Foaming Sugar Scrub

Agree with Paprik - water activity with making controls would prob work for self life tho 70% sucrose would leave potential fungal gap. - if preserved, suggest you shoot for that target. FA releasers and phenoxy not so useful in that context. what’s pH?
With packaging - what is expectation of consumer water addition/contamination/

PhilGeis

Member

March 7, 2022 at 10:12 am in reply to: Does this product need a preservative ❓

Glycerine from Sapogel + 2% is prob irrelevant - great if you could get Aw data but I know that’s not generally available.
What’s powder bioburden?
Hot fill ? Does it appears to take up water?

PhilGeis

Member

February 23, 2022 at 1:28 pm in reply to: Precipitate in skin cleanser

The quality of their product is not the quality of your product. Can you share your risk assessment?

PhilGeis

Member

February 22, 2022 at 5:48 pm in reply to: Precipitate in skin cleanser

MurtazaHakim said:

4% w/v of CHG is the active ingredient. A formulation with such a high % of CHG should not require any other preservative.

Wrong. Or perhaps you can prove it.

To note in your “proof” - https://www.cambridge.org/core/journals/infection-control-and-hospital-epidemiology/article/outbreak-of-burkholderia-cepacia-bacteremia-caused-by-contaminated-chlorhexidine-in-a-hemodialysis-unit/85154B587466D8DD5BFC9F9971CDF95E

https://academic.oup.com/jimb/article/42/6/905/5995474?login=true

and many other such reports in google scholar.

PhilGeis

Member

February 22, 2022 at 11:56 am in reply to: Thickeners for Liquid Soap

Not only will phenoxyethanol not cover fungi and Gram positive bacteria well enough - if diluted 1:10 as you indicate, you’ll have only 600 ppm - and inadequate level in any case.

Will you have the consumer dilute?

PhilGeis

Member

February 21, 2022 at 8:48 pm in reply to: Precipitate in skin cleanser

what is the preservative?

PhilGeis

Member

February 21, 2022 at 7:54 pm in reply to: Precipitate in skin cleanser

CHG is a poor preservative.

PhilGeis

Member

February 19, 2022 at 10:49 am in reply to: sodium hydroxide soln ingredients.

Not “purpose”. Those are not added.
Na Carbonate is a natural contaminant of NaOH - a product of CO2 from air and NaOH.
NaCl is a feedstock for NaOH production - prob left over from that process.

PhilGeis

Member

February 18, 2022 at 4:09 pm in reply to: Efficacy comparison of same level of total formaldehyde from formalin vs DMDM hydantoin

2500/2000/1000 ppm respectively with EDTA

PhilGeis

Member

February 18, 2022 at 2:23 pm in reply to: CMIT MIT solution stability in CAPB

Yes.

PhilGeis

Member

February 17, 2022 at 2:45 pm in reply to: Made one big mistake….

Please understand - it is impossible to assure a complete absence of reaction to any consumer exposed. Big companies develop products designed and tested globally to sell millions of units for years to diverse consumers around the world. Potential reactions are followed through consumer comments, reports of dermatologists, etc.

Retailers? Many have gone woke and chemophobic and big companies are conflicted. Big company managements are as woke as retailers’, but their technical folks know BS when they’re asked to put it in products.
Example - preservatives, managements of the big guys got together and funded a greenie org. 3G to search for alternatives. 3G claimed great success (see: https://www.sciencedirect.com/science/article/abs/pii/S2352554120305696). What is not reported - they found nothing of substance. But note the BS, typical of parasitic org.s

I appreciate the dilemma folks here face. It’s one thing to parse “natural” but a much more significant to let that constrain preservation. Just passing USP 51 is very poor to no assurance and you should not sleep at night with e.g. natural eye of new to a few organic acids unless you have great control and monitoring over manuf. quality and barrier packaging. You’ll likely never hear of the “harmful” effects - but those are reality.