PhilGeis
Forum Replies Created
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Big cosmetic companies invest very significantly in their water systems - in no way would potable water standards satisfy their water quality specs. With tools such as RO, DI, to ozonation and high heat their water systems are better than many pharma operations.
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PhilGeis
MemberMarch 29, 2022 at 3:26 pm in reply to: Natural preservative replacement for Germall PlusGLDA is biodegrable not natural. Synthetic product of glutamic acid.
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Assume hard surface cleaning. Recall such products are sold (esp. in southern US and ethnicity) on basis of three functions
1) cleaning and that can be judged by you in practical testing, and
2) fragrance - esp, in use
3) “bloom” - the burst of white opacity when added to water (in a bucket)..These usually have additional surfactants and many have just enough pine oil to for the smell - sacrificing #3.
https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/pine-oil
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For cleaning? As a cleaner - test it.
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PhilGeis
MemberMarch 28, 2022 at 1:10 pm in reply to: Chlorine removal Cleanser/Shampoo - IngredientsNot aware of any Na thiosulphate use as cosmetic preservative. It’s a reducing agent.
Agree - it’s only effective vs. remnant hypochlorite in solution. Does not reverse existing reaction with hair protein.
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PhilGeis
MemberMarch 27, 2022 at 10:18 am in reply to: Preservative quantity suggestion for 0.5% allantoin+0.25% tetrasodium EDTA solutionProb ok.
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PhilGeis
MemberMarch 26, 2022 at 2:56 pm in reply to: Preservative quantity suggestion for 0.5% allantoin+0.25% tetrasodium EDTA solutionCan you describe packaging? Gram + (staph) is largely an in-use risk.
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PhilGeis
MemberMarch 26, 2022 at 2:34 pm in reply to: Preservative quantity suggestion for 0.5% allantoin+0.25% tetrasodium EDTA solutionnot much - but test the product. Gram negatives are you biggest worry.
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PhilGeis
MemberMarch 26, 2022 at 12:52 pm in reply to: Preservative quantity suggestion for 0.5% allantoin+0.25% tetrasodium EDTA solutionno - 0.5% phenoxy/0.3% cap hydroxamic acid. Be aware - this does leave a paper weakness vs Gram positive bacteria.
Prob not see - as in color or phase stability - but in AET testing.
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PhilGeis
MemberMarch 26, 2022 at 11:22 am in reply to: Preservative quantity suggestion for 0.5% allantoin+0.25% tetrasodium EDTA solutionTry 0.3/0.5. Have seen stability issues with EDTA and another hydroxamic acid Zn complex ZPT . Don’t know if efficacy impacted. Suppose AET will reveal.
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PhilGeis
MemberMarch 26, 2022 at 11:03 am in reply to: What amount of caprylhydroxamic acid+0.5% phenoxyethanol will have the same anti fungal effect as…It is formula dependent - but doubt there are enough data to answer esp. as testing offers qualitative rather than quantitative assessment.. Think 0.3-0.5% for Capryl hydroxamic acid.
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chrystad72 said:
Hello! I hope Im not derailing this thread too much but just wanted to ensure Im not misunderstanding this comment. Is the suggestion to add Optiphen into the water phase and then combine the oil phase? Apologies in advance if Im misunderstanding this. Thanks!
Right
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PhilGeis
MemberMarch 21, 2022 at 2:57 pm in reply to: Chlorine removal Cleanser/Shampoo - Ingredientssure others have more info - certainly fade hair coloring but prob needs repeated exposure to really damage
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PhilGeis
MemberMarch 21, 2022 at 2:36 pm in reply to: Chlorine removal Cleanser/Shampoo - IngredientsChlorine (hypochlorite) - it’s very reactive with protein. If uncomplexed, you can rinse it away - otherwise it’s prob complexed with hair protein.
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PhilGeis
MemberMarch 21, 2022 at 1:18 pm in reply to: Chlorine removal Cleanser/Shampoo - IngredientsGreen hair - usually attributed to copper. EDTA should help to some extent. https://europepmc.org/article/med/7555100
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The Jergen’s preservative system would be effective against the bug- as would 0.5% phenoxy. The issue is apparently failed manufacturing hygiene against which no preservative system would hold up. That failure might be as obscure as the use of a contaminated raw material or swab detection of the bug on a product contact surface (with no detect in product) or actual product contamination.
Also consider that a company like Jergens would function at a more demanding spec and testing protocol than many here would apply and would reject and recall based on any isolation without looking for a retest excuse to blow off the finding.
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Graillotion - that assumption is incorrect. There is no preservative system that can’t be compromised. The weak, PC systems like leucidal are much more vulnerable - and those using them are usually less capable of detecting contamination and in some cases more likely to compromise in quality.
Jergen’s uses good systems a=but apparently failed in manufacturing hygiene. It is a surprise as I know that these guys are pretty sound. But it takes only one compromise, and the kevel of testing they invest may have found contamination that others would have missed.gergoviae - formerly Enterobacter has been a tough one for creams and lotions.
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PhilGeis
MemberMarch 20, 2022 at 3:26 pm in reply to: Parabens Are a Safe, Effective Preservative Undermined by Public Outcryright Perry - with retailers, even more than public outcry
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PhilGeis
MemberMarch 20, 2022 at 3:23 pm in reply to: A Plant Hygienist Ensures Manufacturing Quality & Product IntegrityFor those interested, curriculum is being established with Univ Cincinnati
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PhilGeis
MemberMarch 19, 2022 at 2:38 pm in reply to: How to formulate alcohol and PG free natural “rogaine”Right Graillotion.
Good grief, that report is absurd. “hardly show any adverse reaction” - looking only at electrocardiogram?
Here’s a relevant publication from that same French clinical site (best known for sleep research) in a low tier journal. It’s pretty absurd too and shows you can find somebody to publish anything.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681103/
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Please recall glycols can induce irritation. I am familiar with a clinical study of minoxidil in glycol vehicle that provoke very significant irritation. -
PhilGeis
MemberMarch 19, 2022 at 1:39 pm in reply to: Organic Grape Alcohol 190 proof as a Preservative?“Organic Grape alcohol” - for a functional purpose, it’s just ethanol and you need to make sure it’s good alcohol. Alcohol itself can be contaminated.
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PhilGeis
MemberMarch 17, 2022 at 8:20 pm in reply to: Dermosoft® decalact deo MB …. Now available small pak.I’d not get carried away with the efficacy claim
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Aquacar IG50 - glutaraldehdye - is good chemically. At alkaline pH , it’s a good biocide at alkaline pH but degrades rapidly.
Not sure it has necessary EPA registration to be used in household product context so may not be legal for this in US. -
Mg hydroxide is pretty insoluble.
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PhilGeis
MemberMarch 16, 2022 at 10:27 am in reply to: Dermosoft® decalact deo MB …. Now available small pak.wonder at data - no way this is “natural”