Forum Replies Created

  • Mamun

    Member
    September 18, 2018 at 4:38 pm in reply to: Help with my Gel

    Use freeze fried aloe vera powder which is a concentrationo 200:1. It means 1 gm of aloe powder is equal to 200 gm of aloe gel. Dissolve as required of powder in water, generally 1or 2gm of powder in 1000ml of water. It forms gel like substance but unstable and become watery after 10-15 days. Use carbomer as gelling agent nd neutralize it in pH range 6-6.5. Proceed making 1-2% carbomer gel in 1 litre of water following adding 1 gm of aloe powder in 100ml water. Use potassium sorbate/ sodium benzoate as preservative. 

  • Mamun

    Member
    August 10, 2018 at 3:13 pm in reply to: Which Co-Emulsifiers work well with Stearic Acid (Emulsifier)

    I think it’s best to use Tween/Span emulsifier system but u need to use the concentrations of tween-span according to total HLB value of the oil phase. Use HLB formla for emulsification.  

  • Mamun

    Member
    December 6, 2017 at 9:08 am in reply to: Stable Hydroquinone Cream formulation.

    Dr. Bob… is it due to the effect of pH of the media on ascorbic acid? as far as I know in the pH range of 1.0–4.4, the decomposition rate of ascorbic acid increases, while at pH 5.4–7.2, it decreases. due to alkaline pH, hydroquinone rapidly oxidized,tht’s why I kept the pH of the emulsion at 5-5.5. 

  • Mamun

    Member
    December 5, 2017 at 9:04 am in reply to: Stable Hydroquinone Cream formulation.

    Bill_Toge can u plz explain why ascorbic is responsible for discoloration? any other ingredient instead of sodium erythorbate?

  • Mamun

    Member
    December 5, 2017 at 9:02 am in reply to: Stable Hydroquinone Cream formulation.

    Belassi it changes to reddish brown and ultimately black .

  • Mamun

    Member
    December 5, 2017 at 4:27 am in reply to: Stable Hydroquinone Cream formulation.

    Bill_Toge , it discolors after 2-3 days. I need to preserve the formulation for at least 1 and 1/2 yrs.

  • Mamun

    Member
    December 5, 2017 at 4:24 am in reply to: Formulating Gel at low pH

    thank u, Bob! :)

  • Mamun

    Member
    December 4, 2017 at 12:22 pm in reply to: Kojic Acid Cream

    kojic acid is unstable and discolor at alkaline pH (recommended pH range 4.5-5.5). I recommend if u insist using MAP, then u should work with kojic acid dipalmitate as it has broader pH range and more stable than kojic acid.

  • Mamun

    Member
    December 4, 2017 at 12:00 pm in reply to: Formulating Gel at low pH

    Great! thank you so much! is Lubrizol Carbopol Ultrez-30 compatible with electrolytes?

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