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Purpledusk said:

Try Natural solubilizer Clear plus by Dr Straetman it’s  PEG-free and gluten free , Solubol could work too depending of the essential oil I know the solution is clear using rosemary EO although it gets milky with some others, you will need to experiment with mint to find the right ratio, the seller recommends 1:4 (EO/solubol) but from experience I read you’d need to add more for a clear product.

I used this for Propolis in 1:1 ratio for a propolis mouthwash, seems to work pretty well at keeping propolis in solution without resins precipitating.

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ngarayeva001 said:

Funny enough, for many products that include tocopheryl acetate, it isn’t even mentioned in the marketing story. It’s in so many products!

I think a lot use it as an antioxidant for the oils - but there are plenty of better antioxidants for preventing oil rancidity.

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The lower the assay the more you need to supply the ingredient you are after.

The maths is simple: What you want, divided by what you have, multiplied by 100.

So, 69 %/28% x 100 = 246.4% which clearly will not work.

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I suspect this is a new compounds that may be used nutritionally - The tridocosahexenoate oleate is most likely one or two docosahexaenoic acid and one or two oleic acids attached to a triglyceride backbone.

I have come across similar in infant nutrition called OPO being oleic-palmitic-oleic fatty acids attached to a triglyceride backbone.

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Royal Jelly will darken over time owing to the maillard reaction. You will need to work around this.

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Activated carbon is very abrasive - you should be cautious about using activated carbon. We are currently having some toothpastes tested for both abrasive and whitening. We should have the results back in a couple of weeks.

However, you do need to consider why the hydrated silica is there - is it an abrasive grade or is it perhaps a viscosity modifier. If you are removing it as an abrasive, you may not need to replace it. If it is used as a viscosity modifier, then you need to consider your options carefully.

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I work for a toothpaste manufacturer. We removed the paraben preservatives quite some time ago and swapped over to totarol; however the amount used is more for claim than for preservation and to use up some existing stock that was bought for a customer and never used.

We have found that our aseptic manufacturing procedures, combined with high pH (8-9.5 depending on formulation), and low water activity does allow us to manufacture without the use of preservatives.

I would add to that, until you have completed your post manufacturing micro, micro assays on all incoming raw materials and your stability trials you should not attempt to release a product unless you are confident it will not spoil.

We have a three year shelf life on our products, but we have tested and can show our products are safe for six years beyond manufacturing date.

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I have done dietary  supplements for sale in the Chinese market where I have added vitamins/minerals another other ingredients into a fruit juice concentrate and puree. 80-90% puree should have a brix of over 70, if the pH is as low as it is (usually there is plenty of natural acids so tend to be low pH anyway) should should be fine with just potassium sorbate - 0.08%  is usually enough; however, if this is not intended for ingestion, you can increase the amount accordingly. I have checked similar products - and the water activity is quite low (<1 Aw); though you can top up with glycerol instead of water if need be.

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@Pharma - I thought Coty was responsible for this abomination? Givaudan and Ferminich involved too?

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jeremien said:

O/O emulsion interesting concept. I already know about  W/W emulsions.. 

That’s two new thing I have learned today!

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Perry said:

@Dtdang - of course, being misinformed about a subject is usually worse than being uninformed about a subject.

So true - Misinformed means you are arguing with a brick wall. At least you can educate the uninformed.

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lactobacillus will not extract anything from the plants; but what it will do is ferment any sugars to alcohol and lower the pH.

Others doing this are purely doing so to offer the liquid that contains the probiotics; some will separate and dry and mill the plants.

To be honest, there is no benefit to doing this other than claiming some marketing BS. The use of lactoferments is more of dietary use than cosmetic.

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Creatine and creatine monohydrate are essentially the same thing. One is anhydrous the other is hydrated. Unless you are using this in a dry powder, it isn’t going to make any difference.

Even if you do use it in a powder, anhydrous will turn to monohydrate quickly enough. It is a fairly hygroscopic material

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@”Dr Catherine Pratt” Thanks for your suggestion. I’ve just had a 25 kg sack of Kaolin (Halloysite) clay dropped from a rep at Axieo.

I’ll update how I get on - I guess I will need to add more than I used for titanium dioxide.

Thanks again.

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@”Dr Catherine Pratt” A white clay such as kaolin? Or do you have a preferred white clay?

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That’s the problem with marketers and management - they want a lab to look like something out of the movies that they can show off to prospective clients and not something that looks, as @Duncan says, a glorified kitchen with some measuring equipment.
I’ve done a lot more with a lot less than people would think.  

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L-ascorbic acid is the true vitamin C. USP just refers to the United States Pharmacopoeia, the standard to which it is tested. Ascorbic acid, Ascorbic Acid USP, Ascorbic acid BP, L-Ascorbic acid (with or without BP/USP) is all the same thing.

D-ascorbic acid is often sold as Erythorbic acid. It’s much cheaper and tends to used in foods as an antioxidant.

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Google can be your worst enemy at times - its always hard to find the authoritative information and if you don’t know the names of the equipment to search for, you can search forever.

I’m not looking for cosmetic use - I tend to work in the dietary supplement industry and there seems to be a lot of interest in Liposomes in the industry at present. Since preparation is the same whether it is cosmetic or pharmaceutical…. I just thought I would ask.

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The company I work at has a sequential numbering system but not much else and it all somehow works.

In the previous database system, we had separate codes and separate areas for raw materials, packing materials, finished products etc.

The new ERP system doesn’t seem to differentiate that easily - all areas are in one page only. As long as you know what you are searching for and can isolate the data interrogation to the items you are after, it is fine.

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Happy Birthday, old chap.

4/4 is lucky for some, unless you are Chinese!

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@Bozchemist

Thanks for that. The Guar/Xanthan blend is a TIC gum product, which along with the Acacia gum, worked very well when making a stable emulsion.

Re Flavours being microemulsions (esp soda) yep - I did know that. I worked as a sales rep for a flavour house for a year. I sucked big time at sales and decided to go back to doing what I enjoy the most - being a lab rat!

Cheers

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@bobzchemist - I wish I had a like button for that! I will have to remember that.

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Thanks for your comments @bobzchemist.

Silica - I have to use this as part of the formulation anyway since the customer wants to make the Silica claim (about 47% Silica)  and that was why I was wondering whether I could use Silica to use a Pickering emulsion. I think the Silicon Dioxide we have at work is Aerosil (need to check the type) which is fumed silica (I believe, but happy to be corrected on this), and I like the idea of the Calcium Silicate.

I did do a nutritional emultion a year or two back using roughly 1/3rd Sugar, 1/3rd Oil, 1/3rd water using gum arabic 2%, and Guar/Xanthan blend at about 0.2% and this created a nice mayonaise like emulsion.

I guess I could try:

• Acacia gum 2%
• Guar/Xantham blend 0.2%
• Silica 3.5%
• Oil 2%
• Everything else QS to fill

I will let you know how I get on. Thanks for your thoughts

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The Ester-C that is often sold is a Calcium Ascorbate-Calcium Threonate complex bound with an ester bond between the two.

I think the original Ester C is under patent, but I think Monarch sells a version of the Calcium Ascorbate Calcium Threonate but unsure whether this is just a blend of Ascorbate and Threonate or whether this is actually ester-bonded.

I’ve only worked with this material in dietary supplements creating a chewable tablet so am unable to advise on the rest of your questions

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Regarding Stevia - you can source Rebaudoside A, which is much sweeter than Stevia alone and allows you to use less of it. Most of the stuff I have found is very fine - almost talc-like

in the USA, contact Cargil, if elsewhere in the world, contact Layn in China. They do some very nice product - and perhaps look at their Monk fruit/Reb A blends