greensara
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Update: We used a 10% dilution and a new electrode. Slope was around 90, and numbers were spot-on so it appears that the electrode was the culprit. Ph turned out to be very close to our intended mark. Thank you so much for the replies - great insight and suggestions I’ll keep in mind if this should come up again.
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@Belassi, nanodiamonds have attracted so much attention for the very reason that they are so biologically compatible. The government is funding research with nanodiamonds as safe alternatives to quantum dots for bioimaging and as low-toxicity vehicles for targeted drug delivery. Believe it or not, nanodiamonds are literally all around us (some the result of cosmic collisions millions of years ago, and are even created when you burn a candle-albeit they are burned up in the process).
@MarkBroussard just using HA as an example. Due to the potential for creating ‘reservoirs’ and slow release of active ingredients, is it not feasible that functionalizing the surface of the diamond could magnify/extend the benefits of HA over a period of time? Yes, the cost would be significant but I find it absolutely fascinating and still wonder if it is not the next generation of cosmeceuticals…assuming companies can carefully formulate and craft claims so as not to be considered a drug. In fact, the number of companies now offering cosmetics containing ‘diamond dust’, ‘diamond hydrosol’ or nanodiamonds is rapidly expanding. Diamond-based ingredients are now even carried by suppliers that cater to home crafters (Formulator Sample Shop, I think?). None of the claims are substantiated, and some just don’t make sense, but its use is nonetheless on the rise.
@Perry I think you answered my question to large degree: If there is a notable effect that is the result of an ingredient interacting with the skin metabolism, then the products would technically be drugs. What a fine line. I was under the impression that making claims of skin penetration was asking for trouble, but perhaps it’s dermal penetration that would pique the interest of the FDA? I would argue that plenty of products offer ‘notable effects’, although I wouldn’t know if it was a direct result of interaction with skin metabolism. Interesting.
