[granmasutensil]

DMSO is used in high concentrations for arthritis creams, and have been vets applying it topically at 70-100% strength for decades. I believe the issue is more what is being used with it and purity. Water a formulation with DMSO causes DMSO to heat up on skin contact which can cause discomfort or irritation to some.

But I saw a product paper where DMSO was used as a negative control for a hair active. A 10% DMSO solution significantly suppressed viability/metabolism ofHFDPc and ORSc proliferation. So should DMSO be avoided then at all costs for topical hair products?

http://www.nardev.com/UploadSection/ProdCat-276-1446515551.pdf

Propylene glycol also causes irritation commonly in the large amounts as a solvent in hair products which can also speed hairloss.

So the question is what are the best/safest solvents for specifically hair topicals that aren’t likely to cause irritation/promote further hairloss?

[granmasutensil]

Ah thank you. If I could ask one more question. Would fully buffered sodium phytate be fine in this application?