Forum Replies Created

  • formulatorN00b

    Member
    December 19, 2021 at 5:13 pm in reply to: Are glycols like pentylene glycol soluble in oil?

    Pharma said:

    Lipophilic glycols are oil soluble/miscible. Pentylene glycol is just in between water and oil soluble. Shorter chain ones, like the others you mentioned, are only alcohol andwater soluble. These may be incorporated using emulsifiers/co-emulsifiers.
    This Ordinary product likely contains pentylene glycol as part of SymSitive (+ 4-t-butylcyclohexanol) and therefore, the amount should be in the low % range which is likely low enough for full dissolution in the oil base.

    Thank you so much for this answer! That makes sense to me.  

  • formulatorN00b

    Member
    August 27, 2018 at 11:51 pm in reply to: Formulating a Foaming Vehicle for a Topical Leave On?

    Hi there, I just wanted to add some clarification to my intentions with my post. I’m not interested in marketing this product, it’s for my personal use of my skin condition.  I am on dermatologist approved treatment for my condition, however it does not keep me completely clear  High percentage niacinamide/nicotinamide products have previously worked well with my medication to keep my skin clear, they just are difficult to spread because they are watery and absorb too fast to apply everywhere that I need them.  They also don’t tend to layer very well.  

    That said, I agree the foaming aspect is problematic for compromised skin and I suspect I will have to go through a lot of trial and error with this.  I appreciate your input and I’ll see if I can find alternative options that may allow me to apply this active on a large part of my body without being tedious or excessively expensive.  

Chemists Corner