

DRBOB@VERDIENT.BIZ
Forum Replies Created
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sorbitan monooleate even better
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Brij 721-nice slip on wet skin
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DRBOB@VERDIENT.BIZ
MemberApril 3, 2021 at 7:44 pm in reply to: penetration enhancer combined with HMW hyaluronic acid= similar to LMW HA?You need a microemulsion using Oleic Acid ;ps of 25 nm should be transparent if you want the latter.
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take a sample from production prior to addition of oil/surfactant blend and add latter in the lab to see if levels are correct:you can adjust for production batches.if necessary.
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DRBOB@VERDIENT.BIZ
MemberApril 1, 2021 at 5:07 pm in reply to: Can these penetration enhancers be used at a low pH?ethoxy diglycol has skin irritation issues so use level restricted as per application via CRB-dmi has odor in creams/lotions which can be masked but suggest going Green with pentylene glycol ie Hydrolite 5 Green-Symrise
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DRBOB@VERDIENT.BIZ
MemberApril 1, 2021 at 4:39 pm in reply to: How much does adding nonionic surf impact shampoo mildness? / PH driftAlternatively you can add a foam/lather booster ie 1-2% active amine oxide
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I worked for a large, global company - to qualify systems and test, we conducted tests on products recovered after consuner use from each of the major geographies. I’ve worked with other companies who targeted 1000 recovered samples - not for every product but for systems and to qualify their preservative test.I did the same for major Pharm Co doing new product Development on WW basis.You can probably guess the company-now making Covid single dose vaccine.
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At what percentage have you used DMDMH?
And generally, for what sort of products?-CREAMS/LOTIONS @0.5% WT/WT%-NO longer use it due to formaldehyde release as most customers want Form-free.Also used Gydant Plus at lower level 0.3% .Creams lotions gels etc-
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We have sampled from the field to verify.How much do you do and how many samples ?
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you need to supply more info—hair gel for which audience—hair type/s-product type styling gel conditioner?
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You can also use Poly amides such as Seppmax zen good rheology/thickening and very easy to use.
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We have used DMDMH alone in a myriad of systems ie creams lotions gels etc with products having micro-integrity for 3+ years via OTC/USP preservation testing. Unnecessary Overloading of a preservation system can lead to skin problems such as contact dermatitis and so on.Preservative as rule of thumb should be < 1.0% wt/wt.
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DRBOB@VERDIENT.BIZ
MemberMarch 10, 2021 at 4:40 am in reply to: Chelating agent vs cationic surfactantscitric it is tribasic
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DRBOB@VERDIENT.BIZ
MemberMarch 10, 2021 at 1:39 am in reply to: Need formulating services? Here are some contactsVERDI ENTERPRISES
http://www.verdient.biz. drbob@verdient.biz
SKIN CARE HAIR CARE ORAL CARE OTC SUNCARE ANTACIDS DERMACEUTICALS -
agree as we are responsible for product integrity and safety.You need professional stability testing which is not expensive or you could invest in Tempered Oven/s and refidgerator for low temps ie freeze/thaw etc
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you may not need another DMDMH is broad spectrum.Only problem is formaldehyde releaser
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Vitamin E @0.1 to O.5%
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DRBOB@VERDIENT.BIZ
MemberMarch 9, 2021 at 10:09 pm in reply to: Chelating agent vs cationic surfactantsUse a weaker chelate like gluconolactone
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Carbomers are anionic polymers and incompatible with cat ionic oriented
ingredients:Also total ionic additives have to be kept lower compared to emulsions made with xanthan gum. -
Both are good:we routinely use both in combination..
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agree With CC Triglyceride you get a twofer-emollient plus preservation boost
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DRBOB@VERDIENT.BIZ
MemberMay 10, 2020 at 6:58 pm in reply to: Is my formulation including too much or would this be ok?Resveratrol is not water soluble but you can add to oil phase by pre-dissolving in surfactant emulsifier.Also Trans is active form which flips to cis form in storage.Best to use Tiagra Cellcaps encapsulated. which can be added at the end to avoid headaches.Also you have too much in your formula.
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DRBOB@VERDIENT.BIZ
MemberMay 10, 2020 at 3:49 pm in reply to: sodium benzoate and gluconolactone as a broad spectrum preservative?you bet use at 1-1.5% w/w-ph will also buffer at 5-Geoguard Ultra Lonza benzoic acid and gluconolactone.
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The carbomer has to be neutralized and lowered 3% is too much 1% should be enough with 1.1% triethanolamine
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DRBOB@VERDIENT.BIZ
MemberMay 9, 2020 at 5:14 pm in reply to: Toilet Bowl Cleaner formulation Need helpReplace HCL with Citric and add 2% nonionic surfactant Neodol 25-9 or another brand