• Formulating

  Chelating agent vs cationic surfactants

  Posted by abdullah on March 6, 2021 at 6:16 am

  Can we use chelating agents like tetrasodium EDTA or sodium phytate with cationic surfactants?

  abdullah replied 3 years, 1 month ago 4 Members · 10 Replies

  • cationic
  • chelating-agent
  • surfactant
• 10 Replies

• 

  pharma

  Member

  March 6, 2021 at 6:19 am

  Depends.

  Some combinations may form insoluble salts, especially polymers.
• 

  abdullah

  Member

  March 7, 2021 at 2:19 am

  @Pharma i wanted to add ethyl Lauroyl Arginate HCl and EDTA in lotion both for preserving the product. They also formed salt as photo. 
  Does it mean they dont help the preservative system anymore? 

• 

  pharma

  Member

  March 7, 2021 at 8:06 am

  Abdullah said:

  …Does it mean they dont help the preservative system anymore? 

  Correct.

• 

  abdullah

  Member

  March 7, 2021 at 10:58 am

  @Pharma thanks

• 

  LincsChemist

  Member

  March 9, 2021 at 6:00 pm

  I’ve never personally had any problems with disodium EDTA and behentrimonium/cetrimonium chloride.

• 

  drbobverdient-biz

  Member

  March 9, 2021 at 10:09 pm

  Use a weaker chelate like gluconolactone

• 

  abdullah

  Member

  March 10, 2021 at 2:59 am

  @LincsChemist interesting.
  Can it be because i am using tetrasodium EDTA?

  Btw i have some BTMS 25 and SPDMA. I will check with these two 
  Thanks 👍

• 

  abdullah

  Member

  March 10, 2021 at 3:02 am

  @”DRBOB@VERDIENT.BIZ” which one is stronger? gluconolactone or citric acid? 

• 

  drbobverdient-biz

  Member

  March 10, 2021 at 4:40 am

  citric it is tribasic

• 

  abdullah

  Member

  March 10, 2021 at 12:37 pm

  @LincsChemist today i did use EDTA with SPDMA and it formed insoluble salt before adding other ingredients. 

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