DavidW
Forum Replies Created
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Take a sample in a beaker and try adding polysorbate 20 to it. See how much it takes to thin it out.
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If you are checking viscosity in-house it isn’t really a pain, not for us. Our ranges are usually more than 500 cps. Typically at least 1,000cps spread.
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So what do you do to make a living?
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I actually have experience with horse and dog products, yes we do it all
As Bob said we would need much more info to give you an opinion. As far as urea changing the texture it is easy enough to find out by making a lab sample. I don’t think it will. The urea will readily dissolve in water if you have water in your product. Allantoin is another good item for healing.
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We never out salt into the formulation itself. This is one of the reason. It will always vary from batch to batch. Even the salt we get causes differences.
We always look up the amount we used last time and start a little lower and adjust till we get it right. Does your spec have a sufficient range ?
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Good luck, let me know if you need any others
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Isn’t it already in liquid form? If so use heat to get it into water.
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Victoria, my business is manufacturing and filling topical products. While we do provide development services we are really backed up right now. Contact Mark, you will be happy you did.
Does Perry take on on independent projects?
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What do you want the pH to be? Doesn’t really matter what the native pH is, just adjust it to what you need.
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If you send me you email address I can email you info. You can PM me with it. Otherwise I will just send you a message on here.
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Rowayton trading is one. When I am in my office I can look for others and get you contact info. What do you have to get rid of?
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There is a section on here with chemists. Look there. I have worked with Mark of micro formulations in here. Give him a shout.
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Bill,
The thing is the final pH needs to be around 3.0 so based on what you tell me regardless of which I use based on the low pH we will still get that smell.
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@Bill_Toge This morning we premixed Na Metabisulfite in water (as we do in our process) and smelled it. It has that sulfur/metallic smell just being mixed in water with nothing else added. The pH drop later on may bring it out more.
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Anyone have any idea why many HQ formulas have a large percentage of Stearic acid in them? I am talking about 12% to 18%??
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Thanks Bob
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Thanks Bob
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Our lab actually does not usually measure the amount of citric acid solution needed for pH adjustments. They usually just adjust to the required range. This project has been a pain in my side. 2% is no problem but this doctor wants a 5%, 10% and either 15% or 20%.
I appreciate your thoughts on trying to help.
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I didn’t realize you were in Australia. I am looking for Gluconolactone and the title of your post was:
“trouble incorporating geogard sodium benzoate and gluconolactone” I thought you were working with it. I can’t find anyone who has it. -
Yes, that was the other smell. Kind of sulfur like. However, sodium metabisulfite is used in most hydroquinone creams to prevent oxidation as well as a low pH for the same purpose.. The same basic formulation using 2% HQ at the same pH does not have that smell. Thank you for your input.
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Need to know what you people think. Made the formula below. Everything looked fine. Lotion was nice and white. Adjusted with citric acid solution to pH 2.5. The product took on a slight yellow tint, not a big problem. It developed a real weird smell, almost metallic like. You could also actually feel this in your throat when smelled. Any ideas what it may be or how to prevent?
Water 43.73 %
Prop Glycol 17.5 %
PEG-40 Stearate 2.0 %
Cetyl Alc. 2.0
GMS 165 5.0
IPP 2.0
Soybean Oil 4.0
Mineral Oil 2.0
Hydroquinone 5.0
Water 3.0
Sodium Metabisulfite 0.5
Cetearyl Alcohol 2.0
Dimethicone 1.0 -
@kimlewinreilly Do you have a source for D-Gluconotactone?
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“how many g/l can you dissolve in SD alcohol or hot propylene glycol? And does it remain in solution as the PG cools?” Not sure, easily find out with Google.
IT does stay in when PG is cooled.
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I have always found with a lot of water in the formula the sal acid drops out. However, I usually work with higher amounts of sal acid.
If you are making a face wash it should stay.
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50% oil phase is huge. Salicylic acid will go into SD Alcohol or hot propylene glycol. You can try other glycols too. However, with so much water it may drop out over time.