[Biochemist]

Personally I’m not a fan of the idea but it’s been done..
https://youtu.be/wkOPQLGD82U

[Biochemist]

@MarkBroussard what is your preferred -retinol ester?

[Biochemist]

Thanks Perry, great article! So jury is still out..

[Biochemist]

@Doreen the few times I’ve posted I’ve wondered what he might say ???. How good would a ‘Ask Belassi’ thread be? ??? I’m sure some of my questions would give him heaps of material!! 

[Biochemist]

@Belassi??????? do you have a blog I could follow? ???

[Biochemist]

Thanks Perry!

[Biochemist]

Good point @SteveW but I just hate bacteria to have one up on me and my preservation strategy before I start ?

[Biochemist]

@Doreen same!! My other oils in formulation are slightly yellow coloured though so hopefully people won’t think the vit C has oxidised ?

[Biochemist]

Thanks @Doreen I’m about to start using ascorbyl tetraisopalmitate so glad this seems to be ok wrt oxidation

[Biochemist]

Please keep us posted what your rep says, I also like using dermofeel PA-3 @Microformulation

[Biochemist]

Thanks @Perry that’s also been my experience thus far.

[Biochemist]

?exactly @belassi it amazes me how putting a simple blend of vegetable oils on your skin is suddenly an amazing anti ageing serum that is full of claims about smoothing wrinkles, promoting collagen synthesis (the list goes on). That’s why I’d like a trusted (few) resource(s) backed by science as my go to when researching ingredients to use in formulations. 

[Biochemist]

Wow @Bill_Toge! Thanks 

[Biochemist]

I’m still a novice but really like Emulgade PL68/50. Olive M 1000 is also great… except for the soaping. Mark Broussard has some good tips on reducing this.

[Biochemist]

Thanks so much @Bobzchemist and @chemnc! Those are both so different so I’ll see what I can get my hands on.

[Biochemist]

Thanks @MarkBroussard -I’m using Emulgade PL68/50 (cetearyl alcohol & cetearyl glucoside) as non-ionic blend so do you think HLB could still be an issue here?  (Also have an anionic in the combination and glyceryl stearate). Oils at 15- 15.5% so I’ll reduce those- thanks for the tip! Probably also need to work on homogenisation step so I’ll look into some better equipment for home use.

[Biochemist]

Thanks @perry I’ll give it a go

[Biochemist]

Thanks so much @Belassi and @Doreen81. Looks like I might need to do some research into better equipment for home use!

[Biochemist]

Great, thanks @Perry. I’ll work on process then. It’s a body cream -What levels of DL Panthenol would you recommend if mine is a little high? Thanks!

[Biochemist]

Thanks @Bill_Toge- in the case where you have a stable product but the preservative efficacy fails, do you change the preservative and repeat stability testing again, or are you fairly confident you have a stable product so only repeat PET? (Assuming your new preservative doesn’t thin your emulsion etc)

[Biochemist]

@em88 for the products that you mention you know probably won’t be stable at higher temperatures, do you only do room temp testing and specify on storage conditions not to exceed that temp? 

[Biochemist]

Thanks, appreciate the tips!

[Biochemist]

Thanks both for the advice, makes perfect sense.
when do you suggest running preservative efficacy testing in relation to stability testing- concurrently or make sure the product is stable then test preservatives or vice versa?
I need the most cost effective way as I don’t have access to facilities or resources to keep paying for multiple tests. 
thanks!!