Home Cosmetic Science Talk Formulating Would L’ascorbic acid dissolve in glycerin?

  • Microformulation

    Member
    September 28, 2018 at 10:21 pm
    1. Get some L-Ascorbic Acid.
    2. Get some Glycerin.
    3. Go into the lab.
    That is how I would get my answer. Searching for “ascorbic acid solubility” would also be a good start.
    Very first result;
  • Microformulation

    Member
    September 28, 2018 at 11:29 pm

    If you look just at the reference, it lists the solubility of L-Ascorbic acid in Glycerin as 0.05 gm/ml which equates to 5% Wt/volume in pure Glycerin or 5 grams Ascorbic acid in 100 ml of Glycerin.

  • ngarayeva001

    Member
    September 29, 2018 at 7:11 am

    I will say it again, you will not get an anhydrous system with glycerin. It is a humuctant not a solvent. You either need to find a solvent or just accept that the formula can’t be stabilized because you don’t have access to derivatives.

  • MarkBroussard

    Member
    September 29, 2018 at 4:56 pm

    Why don’t you try a mixture of 1,3-Propanediol and Glycerin.

  • Majman

    Member
    September 29, 2018 at 5:55 pm

    Hmmmn! There was a report I read where it says it can dissolve in glycerin which is heated… So I had to throw the question to the house 

  • Majman

    Member
    September 29, 2018 at 8:54 pm

    @Microformulation @ngarayeva001 I’m trying to make an anhydrous vitamin c serum and I want a solution that LAA and HA can dissolve in without it being necessarily water which is receptive to heat to enable me Infuse  powdered leaves extract in it in a double boiler then add other ingredients ,mostly antioxidant liquid extract and ferulic acid so I was thinking glycerin could work, then what solubilzer would be ideal in emulsifying vitamin e oil into such a mixture? Thanks. 

  • Majman

    Member
    September 29, 2018 at 8:56 pm

    Meanwhile I can only have access to glycerin, propylene glycol as base solution, would this work? 

  • belassi

    Member
    September 29, 2018 at 9:45 pm

    Look, why don’t you just bloody well TRY IT and SEE instead of asking endless questions! You might learn something.

  • ngarayeva001

    Member
    September 30, 2018 at 7:15 am

    Anhydrous LAA systems are not very pleasant to apply. You either make an aquaneus gel of LAA and HA plus your extracts (that won’t do much) that will be pleasant to apply and oxidize very soon or you make a minimalistic gritty mixture of propanediol and LAA and skip all other ingredients. And it will be so heavy that you won’t need any glycerin. I think that propanediol might be replaced with propylene glycol. Sorry but you cannot have it all when you have such a limited access to ingredients.

  • Microformulation

    Member
    September 30, 2018 at 2:12 pm

    @Belassi Thank you! This is at best 60 minutes in the lab.

  • Gunther

    Member
    September 30, 2018 at 6:39 pm

    You don’t want a mostly glycerin formulation on your skin.
    Pure or highly concentrated glycerin is actually drying to the skin and may cause irritation or even blisters if left on too long.

  • Majman

    Member
    October 1, 2018 at 2:09 am

    Thanks @Gunther

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