Home Cosmetic Science Talk Formulating General Which is the better penetration enhancer?

  • Pharma

    October 27, 2021 at 2:02 pm

    Neither. Propanediol is just a protic solvent and MSM a solid which, due its close relation to DMSO, is often called a penetration enhancer without reliable citation. MSM may have other effects on skin penetration as you can read HERE (not saying that this is a reliable source nor that the results may be extrapolated).

  • Graillotion

    October 27, 2021 at 5:11 pm

    You could look at a small amount of squalane, or glyceryl oleate.

  • emma1985

    October 29, 2021 at 5:57 pm

    I don’t think either are true penetration enhancers the way Dimethyl Isosorbide is, for example. It’s like when people say glycerin is a penetration enhancer. 

  • ngarayeva001

    October 31, 2021 at 4:16 am

    Look up forum’s archives. It was discussed many times.

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