Cosmetic Science Talk

Cosmetic Science discussion forum. For people who want for formulate cosmetics and get advice from other formulators around the world.
*** Click on one of the three Forum categories below to start a new discussion ***

Home Cosmetic Science Talk Formulating Urea-ethanol reaction in skin sanitizers

  • Urea-ethanol reaction in skin sanitizers

    Posted by Anonymous on August 5, 2020 at 1:51 pm

    Hello everyone,
    I am formulating a liquid spray hand sanitizer containing 63% ethanol, 5% IPA, 2% glycerol and 2% urea. As far as I have tested it, it seems to be Ok, but recently I read about the reaction between ethanol and urea to produce ethyl carbamate, a skin carcinogen molecule. Nevertheless, It appears that such reaction takes place when heating urea and ethanol. My question is if it would be considered as dangerous a cosmetic product containing urea and ethanol?
    Thank you all for your comments
    Javier

    Pharma replied 2 years, 9 months ago 1 Member · 1 Reply
  • 1 Reply
  • Pharma

    Member
    August 11, 2020 at 4:33 pm

    Unlikely to happen in your case, too much water present and not enough heat.