Tromethamine instead of TEA for neutralizing carbomers
I was browsing one of our pharmacy suppliers’ stock for raw materials and see that a warning is placed next to the TEA. About TEA itself containing secundary amines that can be converted into nitrosamines, even after application on the skin, an advice for replacing it with tromethamine is given (1 grams of tromethamine per 1,35 grams TEA).
Now that I see the name tromethamine/trometamol, I remember that we indeed neutralized carbomers at school (ages ago) with this instead of TEA (or NaOH).
What is the opinion in cosmetics nowadays on TEA replacement/nitrosamine forming?
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