Home Cosmetic Science Talk Formulating Solubilizing tocopherol and ferulic acid

  • Solubilizing tocopherol and ferulic acid

    Posted by Ifa on March 13, 2021 at 5:12 am

    How can I (or what can I use to) solubilize 1% tocopherol in a water-based serum?

    How can I (or what can I use to) solubilize 0.5% ferulic acid in a water-based serum?

    What if I want to use both in the same formula?

    Thanks.

    Ifa replied 2 years, 11 months ago 3 Members · 4 Replies
  • 4 Replies
  • Ifa

    Member
    March 15, 2021 at 6:13 am

    Hi, can someone please help?

  • microformulation

    Member
    March 15, 2021 at 3:24 pm
    Likely you are not getting an answer since these are fairly broad topics AND they are really Fundamentals you should be educating yourself on, For example, in this case;
    • Tocopherol is not water soluble (although there are some forms altered to be so, but rarely used due to issues with PEG’s. Solubulization is a huge topic which you will gain a great deal of benefit from studying formally. For example, the Gold standard is polysorbates. Does this meet your raw material standard? (https://www.youtube.com/watch?v=kNbgHvi_lqM)
    • There are numerous discussions regarding Ferulic acid. When you read these, you will likely learn of the L’Oreal patent for using Ferulic acid to stabilize L-Ascorbic acid.

    Again, I am just suggesting that you delve deeper into these topics and read all you can. We could just give spot-on answers, but here I fall into the “give a man a fish…” outlook.

  • pharma

    Member
    March 15, 2021 at 6:18 pm

    @Microformulation I couldn’t have said it better 😉 .

  • Ifa

    Member
    March 16, 2021 at 11:23 am

    Likely you are not getting an answer since these are fairly broad topics AND they are really Fundamentals you should be educating yourself on, For example, in this case;
    • Tocopherol is not water soluble (although there are some forms altered to be so, but rarely used due to issues with PEG’s. Solubulization is a huge topic which you will gain a great deal of benefit from studying formally. For example, the Gold standard is polysorbates. Does this meet your raw material standard? (https://www.youtube.com/watch?v=kNbgHvi_lqM)
    • There are numerous discussions regarding Ferulic acid. When you read these, you will likely learn of the L’Oreal patent for using Ferulic acid to stabilize L-Ascorbic acid.

    Again, I am just suggesting that you delve deeper into these topics and read all you can. We could just give spot-on answers, but here I fall into the “give a man a fish…” outlook.

    Thank you for your response!

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