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Protect against frostbite and/or cold weather?
Does anyone remember the names of the ingredient or ingredients that were touted to do this? I used to have this information, but now I can’t find it. (Petrolatum doesn’t count)
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9 Replies
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Lanolin Anhy?????
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The common names of them are crioprotectors or anti-freezers…Or do you need exact examples of them?
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Exact examples would be helpful - but I’ll research the terms you mention also.
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There are plenty of them and they are coming from different chemical families - glycols, oligosaccharides, sugar alcohols, PVA, DMSO, PVP, salts etc. Are you looking it for cosmetic formulation?
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Yes, cosmetic. They want a “prevents frostbite” claim.
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Was it Antarcticine? “Glacial glycoprotein extract” that was touted to have a bunch of skin regenerative effects. I think frostbite prevention was one of them if I recall correctly. I know for sure there was some “cryo-protective” fluff in the brochure I had.
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I guess it would be important to make a decision what kind of products you want to get exactly. There are some of them that are preventing frostbite, another ones are for the treatment of the injured or affected skin or all together in one product for both purposes. I have got some experience in such formulations earlier prepared for the northern countries. And I have found my records what I have used for different forms from heavy ointment to the spray and lotion. The best formulations I could achieve were those where I put a combination of several crio -protective actives.
The oils: I have found the best working are - cedar oil, turpentine, castor oil, shark oil and their mixture as the base.
Acids: Succinic acid and Malic acid. In certain % in formulation they maintain energy processes in cells and penetrate relatively easily. These acids works the best way if you introduce some Glucose in formulation.
Niacinamide - helps to keep on right circulation in cappilaries. Panthenol taken in 5% and up also works great either as additional crio-protector and treatment of already affected skin.
Glutamic acid and it’s salts - bring pleasant warm to the skin.
Salts: I have experienced with Aluminum salts that regularly used for antiperspirant formulations. I have discovered they are great warmers and their ability to stop the perspiration in timely manner helps in preventing frostbite by reducing the water loss.
Glycols - I have used a mixtures including Propylene glycol, Butylene glycol, Sorbitol and Xylitiol.
And finally - I really do like Formic acid in the formulations like these taken in a very small amount.
I have to add, that different formulations are designed for different temperature conditions - the customer should tell you where the product is supposed to be used 32F or 0- 8-10 F - it helps to mix the right combination of the actives.
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@vitalys …. I have been thinking about trying malic acid in a formulation to see if it will synergize with MSM in carrying some ingredients through to the skin cells, what % would you suggest?
But, I am curious at your suggestion of formic acid in formulations. Is it not a skin irritant? If it can be added successfully, it will be a preservative booster, but it’s the allergic reaction to it that worries me. -
@braveheart re: Malic Acid. If we talk the current topic 1-2% would do. However you may use up to 20% and up in some special formulations as professional chemical peels. Please, advice what does MSM mean?
re: Formic acid. As we all know there are no “bad” or “good” chemicals and only a certain amount defines everything and makes any ingredient either a poison or a remedy in Cosmetic Chemistry or Pharmacology. That’s so true about Formic acid. Yes, it’s a well known irritant, but taken in right % in formulation it works great. Again, if we discuss the formulations against the frostbite the formic acid is very helpful to gain desirable results. It depends on temperature conditions where your products is going to be used. The % of this acid would be gradually increased from 0.2% to 1.5% respectively. If your product is supposed to be used 0-5°C you need the less acid while the product is designed for extreme temperatures (-15 /-20°C) you may increase it up to 1,5%. Nevertheless, using only Formic acid is not sufficient to get the law temperature protectant. I used a “cocktail” of actives. You may use for instance cedar and castor oils along with glycols and salts with a touch of Formic acid introduced in a right cream (ointment) base.
P.S. A little bit about allergy - again, almost every chemical has more or less allergic potential, including irritants. I also guess there is a big gap between the allergy and merely the skin irritation - those conditions have different pathogenesis and clinical manifestations.
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