Home Cosmetic Science Talk Formulating Pro-Oxidation of Vitamins and Oils

  • Pro-Oxidation of Vitamins and Oils

    Posted by Anonymous on June 4, 2020 at 4:33 pm

    Hi All:

    Can anyone provide any guidance on the pro-oxidation of vitamins and oils in formulations?  I vaguely remember a vendor talk to me about it a year ago but can’t remember the vendor or company.  After hours of scrolling the net I have come up with very little info.  What I do remember is that use of higher concentrations of vitamins can somehow start a pro-oxidation reaction and therefore destabilize the entire batch.  If anyone has any pointers or can direct me in the right area to research that’d be great!

    ngarayeva001 replied 3 years, 5 months ago 2 Members · 2 Replies
  • 2 Replies
  • pharma

    June 4, 2020 at 7:59 pm

    There are a few reports showing that alpha-tocopherol can act as a pro-oxidant at higher concentrations. What ‘higher’ concentrations mean, differ between publications.

  • ngarayeva001

    June 5, 2020 at 11:19 am

    I saw 0.1%, 0.2% and 0.5% in different sources. I saw 0.5% in L’Oreal’s patent of C,E Ferulic. I personally stick to 0.1% to be conservative. Or just use BHT.

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