• Formulating

  Pro-Oxidation of Vitamins and Oils

  Posted by Anonymous on June 4, 2020 at 4:33 pm

  Hi All:

  Can anyone provide any guidance on the pro-oxidation of vitamins and oils in formulations?  I vaguely remember a vendor talk to me about it a year ago but can’t remember the vendor or company.  After hours of scrolling the net I have come up with very little info.  What I do remember is that use of higher concentrations of vitamins can somehow start a pro-oxidation reaction and therefore destabilize the entire batch.  If anyone has any pointers or can direct me in the right area to research that’d be great!

  ngarayeva001 replied 4 years, 6 months ago 2 Members · 2 Replies

  • chemistry
  • formula development
  • formula help
  • ingredients
• 2 Replies

• 

  Pharma

  Member

  June 4, 2020 at 7:59 pm

  There are a few reports showing that alpha-tocopherol can act as a pro-oxidant at higher concentrations. What ‘higher’ concentrations mean, differ between publications.

• 

  ngarayeva001

  Member

  June 5, 2020 at 11:19 am

  I saw 0.1%, 0.2% and 0.5% in different sources. I saw 0.5% in L’Oreal’s patent of C,E Ferulic. I personally stick to 0.1% to be conservative. Or just use BHT.

Log In to Reply