• Formulating

  Piroctone olamine vs IPBC comparation as anti fungal preservative

  Posted by Abdullah on April 18, 2023 at 4:58 am

  Piroctone olamine has almost the same MIC as IPBC for Aspergillus brasiliensis and it Candida albican according to supplier data.<div>

  If i use it as preservative combined with phenoxyethanol and EDTA at pH 4-4.7, what amount of piroctone olamine will have the same antifungal activity as 100ppm IPBC in same type of formula?

  </div>

  PhilGeis replied 1 year ago 2 Members · 5 Replies

  • ipbc
  • piroctone olamine
  • preservative
• 5 Replies

• 

  PhilGeis

  Member

  April 18, 2023 at 5:53 am

  Familiar with Piroctone olamine as a dandruff active - it’s another hydroxamate chelator. Not much experience as preservative - efficacy, stability, formula interactions, water quality- cations

  • 

    Abdullah

    Member

    April 18, 2023 at 9:43 am

    Ok

    There are claims that piroctone olamine also reduce hair fall and make hair shaft thicker. Thare they true?

• 

  PhilGeis

  Member

  April 18, 2023 at 2:31 pm

  I’ve heard the same for ZPT - data did not support. What are the data for piroctone?

• 

  Abdullah

  Member

  April 18, 2023 at 7:13 pm

  I have seen this one

  https://onlinelibrary.wiley.com/doi/full/10.1111/ics.12737

  • 

    PhilGeis

    Member

    April 18, 2023 at 8:06 pm

    Thanks. Schwartz is an old pal from P&G so I trust the report.

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