New ingredients for heat rubs
Most heat rubs are based on methyl salicylate and/ormenthol and/or Capsaicin as the active, but I am looking for alternatives to these three.
We have used vanillyl butyl ether and this seems to be either effective for some people but not others - but not all people seem to feel the warmth from it; and, seems to be inneffective in products over 6 months old (or at least seems the case with our trial samples)
I have come across methyl nicotinate - which opinions seem to differ on effectiveness. Nicotinic acid will cause a niacin flush if ingested. But will it do the same tocpically?
Are there any other warming active ingredients (or inactive/excipients) I can consider that will have a topical warming action?
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