Home Cosmetic Science Talk Formulating General Microneedling with HA serum - Safety

  • Microneedling with HA serum - Safety

    Posted by raveena on January 21, 2024 at 8:02 am

    Once again I am here seeking a gift of advice from experienced chemists.

    Microneedling for Hair and Skin has become quite a solution for hair loss (there is a lot of following with excellent results with hair loss).

    Then there are a lot of videos on YouTube with women using Microneedling with a depth of 1.5mm with Hyaluronic acid serum. While the results are great I remember pharma mentioning somewhere it should go beyond our skin due to the safety concerns. Are my concerns legit for at least using serum with Microneedling for wrinkles etc?

    As a woman with a little frown and lines, the results look great but nothing is more important than safety.

    PhilGeis replied 1 month, 1 week ago 5 Members · 8 Replies
  • 8 Replies
  • PhilGeis

    January 21, 2024 at 12:43 pm


    • raveena

      January 21, 2024 at 4:46 pm

      Thank you for your reply. The document only explains the dos and don’t of Microneedling.

      So Is it safe to apply Hyaluronic acid while using the dermarollers? The depth of the roller can be .5mm to 1.5mm. How far it would penetrate the skin?

  • PhilGeis

    January 21, 2024 at 5:41 pm

    Doubt you’ll find a risk assessment and it’s a good bet youtubers never bothered.

    • This reply was modified 1 month, 1 week ago by  PhilGeis.
  • markbroussard

    January 23, 2024 at 9:31 pm


    Yes, it is safe to use HA Serum with Microneedling. Several Microneedling devices are designed to coat the needles with a serum during the microneedling session. I have developed serums for these devices and no reports of any issues.

    • raveena

      January 24, 2024 at 1:47 am

      Hi Mark

      Appreciate your time and feedback. I can I guess now go ahead and get a Microneedling session done with HA serum.

    • PhilGeis

      January 25, 2024 at 8:58 am

      Can you offer a risk assessment beyond no reports of issues. MoCRA alone will require a data based risk assessment that folks should already have.

  • Shalu210397

    January 23, 2024 at 9:47 pm

    Hello Sir

    I am working on a trial batch of Cysteamine Hydrochloride Cream and serum (5%). The odour of cysteamine hydrochloride is very bad. How can I remove this bad odour? I added maltodextrin / Lactic Acid to get rid from this odour. Nothing is working. Please guide me on this.

    Thanks & Regards
    Shalu Rana

  • Unknown Member

    January 23, 2024 at 10:53 pm

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