Home Cosmetic Science Talk Formulating Advanced Questions Maximum TDS and CFU/ml for cosmetic manufacturing

  • Maximum TDS and CFU/ml for cosmetic manufacturing

    Posted by hobbiz on August 31, 2020 at 5:06 am

    Hi all!

    For RO Water to make cosmetics, do we have to follow GMP/USP water guidelines which is 1.3 TDS and 100CFU/ml maximum?
    Or we have a easier standard? My RO Water is about 30TDS and 250CFU/ml. For small scale, installing 200L/h RO system following GMP standard is too much, cost about 30.000$ :( 

    Thank you.

    chemicalmatt replied 3 years, 9 months ago 2 Members · 1 Reply
  • 1 Reply
  • chemicalmatt

    Member
    September 2, 2020 at 4:12 pm

    You do not have to follow those guidelines, they are only that: guidelines. The 100 cfu/ml limit is the general standard for USP<61> TPC of cosmetics. If you can live comfortably with those limits of yours, go with it. RO water systems are notoriously susceptible to biofilm buildup too. Backflush with peracetic acid solution and you may see better results.

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