Home Cosmetic Science Talk Formulating General Science Leaching of phtalates - nail lacquer

  • Leaching of phtalates - nail lacquer

    Posted by Anonymous on April 14, 2015 at 10:50 am

    Dear Forum

    I need to perform a quantitative GC-FID method to establish possible leaching of plasticizer in a nail formulation (into water).

    Can someone please help with an applicable method in order to do so?

    Your assistance will be highly appreciated.


    Microformulation replied 9 years ago 2 Members · 3 Replies
  • 3 Replies
  • Bobzchemist

    April 14, 2015 at 2:12 pm

    Good luck with that. You really need to talk to an analytical chemist or two, and I don’t think that there are any here.

  • Anonymous

    May 28, 2015 at 4:47 am

    Hi Bob,

    Hi Fishie,
    GC will work but the method you really need to use is UHPLC with UV detection. It is the very effective method used to do with plasticizers in P.E.T drinking/water bottles. There is more than 30 phthalates that I can think just in my head that could have been used so you want high end equipment for testing.
    Coming from the colour worlds as a colour manufacturer, I have supplied colour to be put into phthalates, so the visual colour or UV colour can be seen when the phthalate separates or leaches out into the water. Great for detection when DBT’s or in very low conc.
    If you can not find a local company to perform this…. Maybe try a local university to do it for you as a practical and for a small donation?
    Hope this helps,
  • Microformulation

    May 28, 2015 at 1:14 pm

    I would contact Douglas Schoon at Schoon Scientific in Orange County, California. He is very firmly positioned int hat market sector and could make some great recommendations.


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