Lactate Buffer at pH 6.0 for urea stability (referenced in study)
I am trying to figure out how this study is creating their Lactate buffer at pH 6.0.:
They reference making it on page 188:
“Lactate buffers pH 4.5 and 6.0, phosphate buffer pH 6.0, and citrate pH 6.0 were prepared according to European Pharmacopoeia (14)”
I checked the European Pharmacopoeia edition they sourced and found no lactate buffers at all.
Here is the full article:
The pKa for lactic acid is 3.86. How is it possible to make a buffer with it at pH 6.0?
Can anyone clue me in here?