Home Cosmetic Science Talk Formulating Cosmetic Industry Starting a cosmetic line Hydrogen peroxide stability

  • OldPerry

    August 19, 2019 at 6:25 pm

    What was your whole formula?

  • Pharma

    August 19, 2019 at 6:56 pm
    Are you saying that you’re trying to mix bleach with hydrogen peroxide or that you want to make a skin bleaching solution containing hydrogen peroxide?
    Depending on the furnisher, hydrogen peroxide is sold with a small addition of stabiliser (usually not enough to be put on the label but sometimes enough to show up in the MSDS). A common base for cosmetic/pharmaceutical use is phosphoric acid which may or may not be complemented with other ingredients for increased stability or corrosion inhibition (like nitrates), other stabilisers are stannates, pyrophosphates, organophosphates, or colloidal silicate. Pure (i.e. non-stabilised) hydrogen peroxide solutions are very unstable and may decay within hours even in the fridge. Stabilised ones remain stable for years at room temperature given certain conditions (meaning, it depends with what you mix them and under exclusion of light).
    Iron salts/ions are your worst enemy followed by oxidisable organic matter, mix hydrogen peroxide with these and you’ve lost the game. The main effects of above mentioned stabilisers are pH control and iron sequestration.
    For more help. do what @Perry proposed, share your formula.
  • 9879088909

    August 20, 2019 at 5:27 pm

    Hi perry here is my formula 
    yes its a skin bleaching cream
    cetyl alcohol - 6
    emulsify wax-4
    stearic acid -4
    Acetenalide - 0.05
    citric acid- 0.05
    hydrogen peroxide - 5 
    Water - qs
    termuric oil -0.5

  • Pharma

    August 20, 2019 at 6:30 pm
    What is the INCI name of your emulsifying wax? There are several different ones ;) . If it’s the one containing boric acid, then this might be the source of hydrogen peroxide decomposition. Regarding stability; how do you know that it’s not stable? Does your container bloat?
    Turmeric oil (mostly curcumin, I suppose) may not be stable and could be another reason why. Don’t mix any plant extracts with your cream.
    The rest should be fine, since all you have left in there is A) stable against H2O2 or B) is a stabiliser for H2O2.
    I don’t know if 0.05% citric acid suffices. Did you check pH?
    • Rachana

      April 5, 2024 at 6:27 am

      If container getting bloat after two three months and bleach cream come out from sealed container

      What to do?

      Please guide

  • Bill_Toge

    August 20, 2019 at 6:49 pm

    your pH needs to be below 4, and you need a chelator plus a stabiliser e.g. sodium stannate, or etidronic acid

  • Pharma

    August 20, 2019 at 7:27 pm

    It doesn’t necessarily have to be below 4 but it might help. Also, you have a stabiliser (acetanilide) and you have a chelator (citric acid). I certainly wouldn’t use a stannate in a skincare product though exchanging citric for etidronic acid might be an option. Some patents propose the use of phytic acid though I couldn’t find any useful scientific literature in this regard. TBH, I don’t know if acetanilide is fine in a skincare product either… there are products such as Refectocil which only use citric acid at a slightly acidic pH and that cream is stable for several months.

  • 9879088909

    August 21, 2019 at 5:29 pm

    Thanks all of u for ur reply. Pharma its bloating after 1 hour or less time. I will try ur suggested ingredients nd will tell u what the results. 

  • Bill_Toge

    August 22, 2019 at 9:16 pm

    forgot to mention, you also need to use deionised water to make the product - preferably 5 µS/cm or less, as traces of metal salts in water can very easily decompose peroxide

  • belassi

    August 23, 2019 at 5:51 pm

    I’m not going to give advice because the idea is so bad. Skin bleaching, to begin with, is a stupid idea, check out what Fela had to say about it in his album Yellow Fever
    For bleaching skin, an older study reported that you need a concentration of between 20 and 30 percent. This is much higher than the 3 percent that’s considered safe for home use. The risks of burns and scars are far greater than any potential skin lightening effects.
    Third, there is a high risk of accidentally creating high explosive substances.

    • Raychemist

      April 5, 2024 at 7:35 am

      what concentration are you talking about in your post?

  • MarkBroussard

    August 23, 2019 at 6:11 pm


    First of all … what Hydrogen Peroxide are you using?  Is it a 50% solution or a 35% solution.  If you are using 5% of a 50% Hydrogen Peroxide, your effective load of HP is 2.5%.  That’s less than what you buy at the supermarket which is typically a 3% HP load.  So, you’d be better off just going to a drug store, buying a bottle of HP and pouring it on your skin.

  • Bill_Toge

    August 24, 2019 at 11:57 am

    @Belassi in his time they were using mercuric chloride!

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