Home Cosmetic Science Talk Formulating Advanced Questions Fluoride in toothpaste

  • Fluoride in toothpaste

    Posted by Herbnerd on October 1, 2020 at 1:47 am

    The company I work for has decided, after a long history or producing non-fluoridated toothpastes, to have at least one fluoridated option. I will be using sodium monofluorophosphate 1000 ppm (0.76% w/w).

    I understand fluoride isn’t particularly stable in toothpaste hence most brands only having two year shelf-life for their toothpaste.

    Should I be adding an overage to account for fluoride loss over time and what sort of overage I should be adding?

    Herbnerd replied 3 years, 9 months ago 2 Members · 2 Replies
  • 2 Replies
  • ketchito

    Member
    October 3, 2020 at 2:04 pm

    @Herbnerd Sodium monofluorophosphate (SMFP) can undergo hydrolisis during storage, and if you hace Calcium chloride in your formula (abrassive), free fluoride during washing will react with calcium rather than binding to enamel. This also happens with Sodium fluoride. 

    There are to ways to reduce this scenario (and usually brands use this to together): increase the amount of fluoride source (to have aprox. 1450 ppm of fluoride), and use a buffer so the pH doesn’t drift in the case you’re using SMFP. 

    Also, I believe the 1000 ppm you mentioned are not the amount of SMFP, but of fluoride ions.

  • Herbnerd

    Member
    October 5, 2020 at 3:25 am

    @ketchito Thank you. This is what I needed to hear. Greatly appreciated.

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