Home Cosmetic Science Talk Formulating Skin Escin …. Allergen of the Year candidate??? (or just bad luck)

  • Escin …. Allergen of the Year candidate??? (or just bad luck)

    Posted by Graillotion on August 9, 2022 at 12:45 am

    So about to add Escin to the next iteration of an eye cream I am working on…and was reading through the mfg provided data…. ONLY TO DISCOVER….IN THEIR PROUD FINDINGS…. 15% OF TEST SUBJECTS REACTED TO IT.

    The product I will introduce…is Edemine…which is lecithin and Escin.  Does lecithin minimize a possible reaction (not logical to me)?


    OMG…. was this just bad luck????

    Here is a ‘copy and paste’ from the mfg material:

    “Cream with 0,5% Escin vs Cream with 0,5% of Edemine®, 20 volunteers for 2 months - daily application.
    Note: Three volunteers didn’t finish the Escin cream application due to an allergic reaction.”

    I also found studies that oral Escin, helped mitigate allergic responses!?

    Pharma replied 1 year, 8 months ago 2 Members · 1 Reply
  • 1 Reply
  • Pharma

    August 9, 2022 at 4:31 am

    People get allergies from everything, more so from plants than synthetics… I don’t think that lecithin could help prevent an allergy. However, aescin formulated with bad mojo might cause irritations. Aescin is a saponin, a ‘herbal soap’, and detergents, as you know, can be harsh or mild depending on how they are blended. Saponins are usually regarded as mild surfactants but sometimes that’s already too harsh for some people.

Log in to reply.