Home Cosmetic Science Talk Formulating Enhancing Penetration: solvents and solubilizers

  • Enhancing Penetration: solvents and solubilizers

    Posted by Chemacrology on March 7, 2023 at 7:23 am

    Please help me learn about the particularly good solvents/solubilizers we can use to enhance penetration:

    • Water
    • Ethanol
    • Propylene Glycol
    • Dimethyl Isosorbide
    • Polysorbate 80
    • DMSO/dimethylsulphoxide (unsafe)
    • Sodium lauryl sulfate

    Tell me about your preferred solvent/solubilizer or penetration enhancer and why.

    Thank you.

    AZIZ_KALUNGI256 replied 1 year, 3 months ago 2 Members · 1 Reply
  • 1 Reply

    March 18, 2023 at 2:48 pm

    I’ve been using propylene glycol at 1% in creams and lotions for penetration enhancement purposes for 3 years now.

    PS: am not a professional formulator but my research led that.

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