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EDTA vs Disodium EDTA
Hi everyone,
I made a mistake while I was formulating an aerosol air freshener.
In my formulation and test trials I used a disodium EDTA that I had available in the lab. At that time, I just read EDTA and didn’t pay attention it was a salt form of EDTA.
Then, when I approved my formula, I asked our procurement department to get me EDTA. So, she did it and found it for $1.54/lb. She got me enough sample for a pilot run.
When I then try this sample in the lab, it wasn’t dissolving in water. I finally realized that I used the salt version in my pretrials and now I have the EDTA (not salt). When I told her that, she went and try to procure the disodium EDTA and she is having difficult to find it and the ones she found the prices are outrageous ($166/lb).Have you ever used in production EDTA instead of disodium EDTA? If yes, how did you solve your solubility issue during batch making?
What would be the implications of using EDTA rather than the disodium EDTA in my pilot run?
Just so you know, I do have DI water in our plant. I am also using EDTA along with Phenoxyethanol as a preservative “package”.
thank you all in advance
Ericka.
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4 Replies
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I don’t know what you have but it is not EDTA.
EDTA is a soluble liquid. -
Hi Belassi,
this is the EDTA I am having a issue dissolving. you will see that in the SDS the it is insoluble in water, then the vendor said that the SDS is incorrect that it is soluble.
i am confused by it.
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Ethylenediaminetetraacetic acid (EDTA), is an aminopolycarboxylic acid and a colorless, water-soluble solid. (Wikipedia)
BUT:
This product is slowly soluble in water at room temperature up to 0.26 M, which is approximately 96 mg in a final volume of 1 ml. The pH of this solution will be in the range of 4 to 6.
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You can neutralize EDTA (free acid) with Sodium hydroxide to make disodium or Tetrasodum EDTA as desired.
But EDTA should be cheap and widely available.
You many need to ask for its brand names like Trilon B (and generics)
https://www.ulprospector.com/en/na/Cleaners/Detail/3690/83903/TRILON-B-POWDER
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